Protein Info for CCNA_03003 in Caulobacter crescentus NA1000 Δfur

Annotation: two component sensor histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 556 transmembrane" amino acids 22 to 42 (21 residues), see Phobius details amino acids 285 to 306 (22 residues), see Phobius details PF02743: dCache_1" amino acids 49 to 270 (222 residues), 58.9 bits, see alignment E=7.9e-20 PF07536: HWE_HK" amino acids 368 to 443 (76 residues), 78.4 bits, see alignment E=8.6e-26

Best Hits

KEGG orthology group: None (inferred from 100% identity to ccr:CC_2909)

Predicted SEED Role

"FIG00484132: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3CB64 at UniProt or InterPro

Protein Sequence (556 amino acids)

>CCNA_03003 two component sensor histidine kinase (Caulobacter crescentus NA1000 Δfur)
MPGLETAEHGLRRRVSSVRGRLVLLTVSLLVPALLAMGFLLASADRESRGRLYQQLLTTA
RALNGAVDRQAATGISVAETLATDEALLAGDWAGFHARARRAMERRTGWIVVADANGQQV
LNTRVPYGRPLPRIQRTPEETKAFLAGRSKVSDLLAGPVAGTPVITVGTPITVKGRFYVL
SYVVDAASFTSVFRQQRVPDTWVATLLDNRQRVIARSRLNEKFTGAQASADMTENLRHST
EGVNRSISLEGVPTRVAYTRSPQTGWTLVVAIPRKELASTVNRSVAVGTGIFLLLLVLGL
WLALVYSRRINRDMRRLVRDASAIGRGESLQPAPRDSLEEIAAVHAALLTASEELKAREE
RQGVMINELNHRVKNTLATVQALARQTFAKVDGAPLGVFTDRLIALSGAHDLLTRTGWRE
ADMAALIEASLGAHGDRVDREGPTVALAPHTAVGLSMVFHELATNSAKYGALSAPGGRVA
LTWRRDPVSDTLFFTWRDVGGPQVIPPASLGFGTRLIESSIRREQKGQARFDFLPDGLVF
EASLPLPEAVRWSNPL