Protein Info for CCNA_02945 in Caulobacter crescentus NA1000 Δfur

Annotation: PAS-family sensor histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 653 PF12860: PAS_7" amino acids 23 to 133 (111 residues), 48.5 bits, see alignment E=3.7e-16 TIGR00229: PAS domain S-box protein" amino acids 141 to 259 (119 residues), 49.2 bits, see alignment E=2.8e-17 PF00989: PAS" amino acids 142 to 253 (112 residues), 46.1 bits, see alignment E=1.8e-15 PF08448: PAS_4" amino acids 147 to 257 (111 residues), 71.6 bits, see alignment E=2.6e-23 PF13426: PAS_9" amino acids 153 to 255 (103 residues), 30.7 bits, see alignment E=1.3e-10 PF00512: HisKA" amino acids 276 to 341 (66 residues), 76.5 bits, see alignment E=5.3e-25 PF02518: HATPase_c" amino acids 388 to 499 (112 residues), 89.3 bits, see alignment E=9.2e-29 PF00072: Response_reg" amino acids 528 to 640 (113 residues), 84.7 bits, see alignment E=2.1e-27

Best Hits

KEGG orthology group: None (inferred from 100% identity to ccr:CC_2852)

Predicted SEED Role

"FIG00484454: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3CBU6 at UniProt or InterPro

Protein Sequence (653 amino acids)

>CCNA_02945 PAS-family sensor histidine kinase (Caulobacter crescentus NA1000 Δfur)
MNAATLVDTHAVDTALQEAFEAAPEGFALFDAEDRCVIWNARYGELWSKWGVTLAVGATF
ESLLLAGLAAGRFPEANGDRAAWLAHQLGRRKLDRIEEIREEFGEYLRFESRRTPAGGLI
TTCANLTNLRRREAQALAARSFLDTIVENTPAMLFVKDGDTGAFLLVNRAAENQLGVPRA
ELLGKSDYDFFPKEQADAFAADDRRVIASGKLVTIDEEPLDTPHNGRRWLQTRKIAIPGE
DGRRHLLVICEDITERKAGAAALAEALQKAEAGSVAKSEFLANMSHEIRTPLNGVIGMAE
VLSRTALDDAQREMMEVILNSGRALNLLLSDILDLSKIEAGGLELSRDPLDLREAITAAV
AVFKAVAESKGLVFRLTFADDFHDHVLGDALRVRQIVANLTSNAVKFTTAGSVIIEARTL
VAEDGRIDLTVSVQDTGEGFDEDSADRLFERFQQADGSVTRKVGGTGLGLPIARRLARLM
DGEISCVAHPGEGATFVFEALFLADGQRTPAASADPAGELALDRRLRVLLAEDHPTNQKV
IGLMLADAADVTVAEDGQAAVEAFEKHAYDVVLMDTQMPVMDGLAAIAEIRRREREAQAR
RTPIISLTANAMPHQVRACLEAGADLHLAKPVSIQGLFATLGAALETRPGGEG