Protein Info for CCNA_02821 in Caulobacter crescentus NA1000 Δfur

Annotation: hipA-related phosphatidylinositol 3/4-kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 444 TIGR03071: HipA N-terminal domain" amino acids 8 to 106 (99 residues), 103.5 bits, see alignment E=2.9e-34 PF13657: Couple_hipA" amino acids 16 to 106 (91 residues), 80.9 bits, see alignment E=8.7e-27 PF07804: HipA_C" amino acids 155 to 388 (234 residues), 141.7 bits, see alignment E=2.8e-45

Best Hits

KEGG orthology group: K07154, (no description) (inferred from 100% identity to ccs:CCNA_02821)

Predicted SEED Role

"HipA protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3CA27 at UniProt or InterPro

Protein Sequence (444 amino acids)

>CCNA_02821 hipA-related phosphatidylinositol 3/4-kinase (Caulobacter crescentus NA1000 Δfur)
MSGPAGLIVRMDGFNLPAGYLASDEARAISFAYDDRYIAAGGPPLSLSMPLEQVSFGDVT
ARAFFDNLLPENDQMQRVMDREGLARDDIVGLLSHLGADCSGAISCLPIGADPIKVPGVL
SEDYELLAPGAIAEIARSLAERQRLPDTITDPSPVAGVQRKIALTHTPQGFAKPRPGRKV
PTTHILKVPETRLRRDARLEAAAARLASALGLDVSIPEAIVIDGVDALLITRFDRVVRDG
VVYRLHQEDFAQAMGLPATLKYQRNGAPGRQFDAQAIARVLDQTEAPALSRTAFLSATIF
NLLIGNTDNHAKNHGLLYRQGRAPILAPLYDLLPSRMNLDFNDQLSFNIGAADHPDAITF
DDMMAFFEVFGMRRAAAARFIENVIKPMIEALERATLGLAGERLKDMDDLIGRETEQLVE
VLGLDVAVRERDYYPKVRHALAPS