Protein Info for CCNA_02414 in Caulobacter crescentus NA1000 Δfur

Annotation: DadA-related amino acid oxidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 338 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details PF01266: DAO" amino acids 8 to 314 (307 residues), 132.2 bits, see alignment E=3.5e-42

Best Hits

KEGG orthology group: K03153, glycine oxidase [EC: 1.4.3.19] (inferred from 100% identity to ccr:CC_2329)

Predicted SEED Role

"Glycine oxidase ThiO (EC 1.4.3.19)" in subsystem Thiamin biosynthesis (EC 1.4.3.19)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.4.3.19

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C908 at UniProt or InterPro

Protein Sequence (338 amino acids)

>CCNA_02414 DadA-related amino acid oxidase (Caulobacter crescentus NA1000 Δfur)
MKLRSGARIAVAGAGALGSAVALRLAQRGFRVTVFDPSPGDANASSVAAGMLAPVSEALF
DPASRNHLDIMKRARDLWPDFARVLGLGLERDGVRIEGSDAWRSEVASRLGALGEPAGAF
IAEDWRIDARAGLLALRGAASEAGAVFRALAVCGFEAGVLELADGGEEPFDTLILATGPG
LRQGEITPETRMLSPIKGQILRLAACDDDGAPVVRGEGVYLAPGAVLAVGATMEHGRDDL
TPDLEATLGLRRAAAALRRDLDLESATVEVGVRVTTPDGLPLVGWSRTPGVMLAVGARRN
GWLFAPLVADMVAAYLTGDNLGPDAAAMDARRFEKPKT