Protein Info for CCNA_02279 in Caulobacter crescentus NA1000 Δfur

Annotation: disulfide bond formation protein B

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 209 transmembrane" amino acids 49 to 67 (19 residues), see Phobius details amino acids 85 to 103 (19 residues), see Phobius details amino acids 112 to 131 (20 residues), see Phobius details amino acids 175 to 201 (27 residues), see Phobius details PF02600: DsbB" amino acids 47 to 199 (153 residues), 120.8 bits, see alignment E=3.3e-39

Best Hits

KEGG orthology group: None (inferred from 100% identity to ccr:CC_2196)

Predicted SEED Role

"Periplasmic thiol:disulfide oxidoreductase DsbB, required for DsbA reoxidation" in subsystem Biogenesis of c-type cytochromes or Periplasmic disulfide interchange

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3CBN9 at UniProt or InterPro

Protein Sequence (209 amino acids)

>CCNA_02279 disulfide bond formation protein B (Caulobacter crescentus NA1000 Δfur)
MTNDDPKVEKAGPAGELEPQATPVRGPAPVEAPAPSIVDRTVDVVTRHWPLMALLSSALL
LAIAHAFEKFGGLAPCHLCLKQREVYWVAGTVGLVGLVLQRTPLWPRLRMPALLLLGAIF
LYGAGLAAYHAGAEWKWWPGPKTCSGGDAAAASNLEAMLKGTADIKPPACDKAAWVFLGL
SMAGWNVLISLKLAAWSVLAAFRKSETPA