Protein Info for CCNA_02220 in Caulobacter crescentus NA1000 Δfur

Annotation: beta-glucosidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00232: Glyco_hydro_1
  • amino acids 39 to 475 (437 residues), 419.5 bits, E=6.7e-130
• TIGR03356: beta-galactosidase
  • amino acids 41 to 469 (429 residues), 493.3 bits, E=3.2e-152

Best Hits

KEGG orthology group: K05350, beta-glucosidase [EC: 3.2.1.21] (inferred from 100% identity to ccs:CCNA_02220)

Predicted SEED Role

"Beta-glucosidase (EC 3.2.1.21)" in subsystem Beta-Glucoside Metabolism or Fructooligosaccharides(FOS) and Raffinose Utilization (EC 3.2.1.21)

MetaCyc Pathways

• neolinustatin bioactivation (2/3 steps found)
• linamarin degradation (1/2 steps found)
• lotaustralin degradation (1/2 steps found)
• linustatin bioactivation (2/4 steps found)
• cellulose degradation II (fungi) (1/3 steps found)
• coumarin biosynthesis (via 2-coumarate) (2/5 steps found)
• α-tomatine degradation (1/6 steps found)
• firefly bioluminescence (2/14 steps found)

KEGG Metabolic Maps

• Cyanoamino acid metabolism
• Phenylpropanoid biosynthesis
• Starch and sucrose metabolism

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.21

Use Curated BLAST to search for 3.2.1.21

Sequence Analysis Tools

See A0A0H3C9V1 at UniProt or InterPro

Protein Sequence (482 amino acids)

>CCNA_02220 beta-glucosidase (Caulobacter crescentus NA1000 Δfur)
MDRSGVSRRALGTLALGGAALGLSACEGPGETDLTPKGRQFPKDFVWGVATAAFQTEGSQ
TADGRGPSIWDVFERVPGHVKNGDTAADATDSYRRYQDDVDLIAGASLSAYRFSMSWSRI
LPTGAGAVNAAGLDHYSRLVDALLAKGITPYATLFHWDLPQGLQDKGGWANRDTAQRLAD
YARAVVERLGDRLKNYIILNEAAVHTVFGHVLGDHAPGLKDAALLGPVTHHMNLGQGLAI
QALRAARSDLSVGTTMALQPCRPAGGPLAFWNRLASDGLDEIWNLAWLDPLFKGTYPKAM
EEPLKGVVRDGDLKTTRQPVDFLGVNYYAPAYVRLDLSAPSKIAAAAAPNSAEQDAFGRH
IDPSGLFEVLDRVRREYGAPKMLVTENGCSDPFSSGPAILDDTFRIKYLRRHLEAVLAAR
EAGCDVRGYFEWTLIDNFEWDLGYTSKFGITTMEAASGRRIPKASYGWFKALAQTGTLPS
SP