Protein Info for CCNA_02069 in Caulobacter crescentus NA1000 Δfur

Annotation: protein translocase subunit secF

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 321 transmembrane" amino acids 21 to 44 (24 residues), see Phobius details amino acids 144 to 165 (22 residues), see Phobius details amino acids 172 to 193 (22 residues), see Phobius details amino acids 201 to 221 (21 residues), see Phobius details amino acids 246 to 267 (22 residues), see Phobius details amino acids 273 to 301 (29 residues), see Phobius details PF07549: Sec_GG" amino acids 43 to 64 (22 residues), 31.5 bits, see alignment (E = 9.4e-12) TIGR00966: protein-export membrane protein SecF" amino acids 47 to 293 (247 residues), 263.4 bits, see alignment E=2.3e-82 TIGR00916: protein-export membrane protein, SecD/SecF family" amino acids 115 to 291 (177 residues), 175.4 bits, see alignment E=1.4e-55 PF02355: SecD_SecF" amino acids 122 to 302 (181 residues), 224 bits, see alignment E=1.1e-70

Best Hits

Swiss-Prot: 39% identical to SECF_VIBAL: Protein translocase subunit SecF (secF) from Vibrio alginolyticus

KEGG orthology group: K03074, preprotein translocase subunit SecF (inferred from 100% identity to ccs:CCNA_02069)

Predicted SEED Role

"Protein-export membrane protein SecF (TC 3.A.5.1.1)" (TC 3.A.5.1.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C9F6 at UniProt or InterPro

Protein Sequence (321 amino acids)

>CCNA_02069 protein translocase subunit secF (Caulobacter crescentus NA1000 Δfur)
MSTPMAWPLIKLLPQKTNLTFVKFARIMAVISATLVVASLIGVFKPGLNLGIDFKGGSVM
EVSTAPRAVDLAKVRTTLEAQGLGDVQVQAFGSPDRALVRFQTPAGGDPGVTLTNVKTAL
KQSLGDPVQFINPSAVGPKVSGELFRSGILALVLAVGLMFVYIWFRFEPQFGLGAVAGLL
HDLILTFGFIVLFKIEFSLNTVAALLTVIGYSMNDTVVVFDRLRENLRKYKKMPLKDVID
LSINEIVSRTIITGVTAIMALTGLAIFGGDALFGFSVVMIFGIAVGTYSSIYVGAPIILL
WGVKRGEEEATPIKLGAASRP