Protein Info for CCNA_01946 in Caulobacter crescentus NA1000 Δfur

Annotation: tyrosyl-tRNA synthetase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 441 TIGR00234: tyrosine--tRNA ligase" amino acids 32 to 438 (407 residues), 373.9 bits, see alignment E=5.5e-116 PF00579: tRNA-synt_1b" amino acids 59 to 353 (295 residues), 251.5 bits, see alignment E=5.5e-79

Best Hits

Swiss-Prot: 100% identical to SYY_CAUVN: Tyrosine--tRNA ligase (tyrS) from Caulobacter vibrioides (strain NA1000 / CB15N)

KEGG orthology group: K01866, tyrosyl-tRNA synthetase [EC: 6.1.1.1] (inferred from 100% identity to ccs:CCNA_01946)

Predicted SEED Role

"Tyrosyl-tRNA synthetase (EC 6.1.1.1)" (EC 6.1.1.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 6.1.1.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B8GWL9 at UniProt or InterPro

Protein Sequence (441 amino acids)

>CCNA_01946 tyrosyl-tRNA synthetase (Caulobacter crescentus NA1000 Δfur)
MNPSHTDQAVLDGPPRQIESRSMSAASSFKSEFLRTLEARGYIHQITHADELDTAAQGGP
IVAYIGFDATAPSLHVGSLIQIMLLRRLQQAGHKPIVLMGGGTTKVGDPTGKDESRKLLS
DADIQANIAGIKTVFSKFLTFGDGPTDAIMVDNDVWLSKFGYVQFLREYGVHFTVNRMLA
FDSVKLRLEREQPMTFLEFNYMLMQAVDFLELNRAHGCVLQMGGSDQWGNILNGVELTRR
VDQKSAFGLTTPLLATASGAKMGKTAAGAVWLNAEQLSPYDYWQFWRNTEDADVGRFLKL
FTDLPLDRIAELEALEGAQINEAKKVLADEATRMAHGEEEARKARDAAEKAFEQGALSAD
LPTYEIAAADLDAGVVLAALFADAGLAGSRGEARRLAQGGGLKVNDKAEADANRLITAAD
LVEGVVKLAAGKKKIVLVKPV