Protein Info for CCNA_01920 in Caulobacter crescentus NA1000 Δfur

Annotation: transcription-repair coupling factor Mfd

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1155 PF17757: UvrB_inter" amino acids 134 to 218 (85 residues), 81.9 bits, see alignment 1e-26 TIGR00580: transcription-repair coupling factor" amino acids 151 to 1085 (935 residues), 1055.3 bits, see alignment E=0 PF21132: MFD_D3" amino acids 390 to 459 (70 residues), 25.3 bits, see alignment 4.3e-09 PF02559: CarD_TRCF_RID" amino acids 483 to 538 (56 residues), 67.7 bits, see alignment 2.7e-22 PF04851: ResIII" amino acids 608 to 764 (157 residues), 40.3 bits, see alignment E=1.1e-13 PF00270: DEAD" amino acids 608 to 770 (163 residues), 87 bits, see alignment E=4.4e-28 PF00271: Helicase_C" amino acids 805 to 912 (108 residues), 69 bits, see alignment E=1.4e-22 PF03461: TRCF" amino acids 1016 to 1104 (89 residues), 85.9 bits, see alignment 6.8e-28

Best Hits

Predicted SEED Role

"Transcription-repair coupling factor" in subsystem DNA-replication or Transcription factors bacterial

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C9F5 at UniProt or InterPro

Protein Sequence (1155 amino acids)

>CCNA_01920 transcription-repair coupling factor Mfd (Caulobacter crescentus NA1000 Δfur)
MSYDAKQIAKAAGGLTLAGAPEGFDALVMADIARARGGLTAFVARDTARAGAFIDALKFF
APEIEAVLFPSWDCLPYDRIGPSSGVSATRMATLSRLARGLGESKAAILVIAAPALLQRV
PTKEVLLRASYAAKVGANVDIKDLERYFAVNGYTRASTVSERGEFAIRGGVIDVYPPAAE
EPVRLDLFGDTLESIRAFDPETQRSTKQLKEIDLLPVSEALLDADGISRFRKGYVAEFGA
PGDDALYAAVSEGGRRAGLEHWLPLFYERMATLFDYLPAGALIGVDNQATEARDERLAMI
QDAYDARASADRKSAYRPLAPEALYLTAEEWERELSDRTHRRFTPFQPQGLDVIDLGAKL
GRVFAAERAQDSVNLFEATADHAKALAAQGKRVLFASWSEGSSERLGTMLADHGLKKIPY
AGYWQAAKANDPKVPQRVVLPLDHGFETDSLAVISETDILGDRLARPRKKRRAANFLAEA
SALTPGDLVVHIDHGIGRYEGLKTLDVQGAPHDCLDLLYGGEAKLYLPVENIDLLTRYGA
ADAENVQLDKLGGAAWQGRKAKAKERLRVMAEGLIQIAAARQLKTVEETDPPSGVFDEFC
ARFPYEETDDQLSAIHDVLEDLSSGKPMDRLICGDVGFGKTEVALRAAFVVAMSGKQVAI
VCPTTLLARQHYKTFKDRFQGWPVKVTRLSRLVTGKEAAETREGLANGQFEIVVGTHAIL
SKQVSFKDLGLVIVDEEQHFGVKHKEKLKELRADVHMLTLTATPIPRTLQMALSGIREMS
IIATPPVDRLAVRTYISPFDPVTLREALLREKYRGGQSYYVVPRIKDLEDIEKFLRTQVP
EVKFVVGHGQMAATQLEDVMTAFYEGQYDVLLATTIVESGLDIPSANTLIVHRADMFGLA
QLYQIRGRVGRSKARAYAYLTTPVEKSLTPSAEKRLQVLQSLDSLGAGFQLASHDLDQRG
GGNLLGDEQSGHIKEIGVELYQQMLEDAVAELRQRQGQEALLEDRGWSPQINTGAAVMIP
DDYVPDLNVRLSLYRRLSEAEQAADREALAAEMIDRFGPLPPETDSLLKVVAIKGLCREA
NVAKIDVGPKGAVASFRGDSYANPLGLMQHVAKNSLIWKVRPDQKVVIKGEWDTPAQRLD
AAEKILTVLAKLAKG