Protein Info for CCNA_01894 in Caulobacter crescentus NA1000 Δfur

Annotation: FAD-NAD(P)-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 543 PF07992: Pyr_redox_2" amino acids 18 to 245 (228 residues), 58.9 bits, see alignment E=1.7e-19 PF13738: Pyr_redox_3" amino acids 19 to 222 (204 residues), 52.7 bits, see alignment E=1.2e-17 PF00743: FMO-like" amino acids 19 to 222 (204 residues), 45.3 bits, see alignment E=1.3e-15 PF13450: NAD_binding_8" amino acids 20 to 66 (47 residues), 37.5 bits, see alignment 6.9e-13 PF13434: Lys_Orn_oxgnase" amino acids 93 to 220 (128 residues), 28.2 bits, see alignment E=3.3e-10

Best Hits

Swiss-Prot: 49% identical to PAMO_THEFY: Phenylacetone monooxygenase (pamO) from Thermobifida fusca (strain YX)

KEGG orthology group: None (inferred from 100% identity to ccs:CCNA_01894)

Predicted SEED Role

"Cyclohexanone monooxygenase (EC 1.14.13.22)" (EC 1.14.13.22)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.14.13.22

Use Curated BLAST to search for 1.14.13.22

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C916 at UniProt or InterPro

Protein Sequence (543 amino acids)

>CCNA_01894 FAD-NAD(P)-binding protein (Caulobacter crescentus NA1000 Δfur)
MDINTSAGPTGAVRRAQAIVVGAGFGGMYAIHRLRQEGLSVLGLEAGGDVGGTWYWNRYP
GARCDVTSIDYSYAFSQAIEQEWTWSEVFAAGSEILAYANFVADRLDLRSAYQFNTRVQT
IAFDDARRVWTLTTDQGQRFEADNLIMATGPLSLPKPVDIPGADRFKGELYRSGKWPHHA
VDFSGKRVGVVGTGSSGIQIVPVVAETCQSLTVFQRTPSFTLPMRNKKVSEDYAAQLKAN
MAGLRAAARTTFTGGVRPLSTRPLFSIPVEERNELMEEAWAKGALQFLGLFSDLLTNAAA
NEIVADFVRDKISQTVKDPVTAEALKPRGYPIYARRPCLDTQYYETYNLPHVSLVDCFEE
PISAFTETGLRTSQREIALDVIIMATGYDALTGPMLAIDITGRDGLKLSEAWRDGPRSYL
ALLMHGFPNLFIIGGPNGPSILANYIRLDELNVDWVVDCILHMQREGLATVEATAEAQTR
WSQTVGEIADRTLYVKADTWYTGTNIEGKPRGFFVFAGGLNRYAEICAGVAAAGYEGCCF
TAR