Protein Info for CCNA_01693 in Caulobacter crescentus NA1000 Δfur

Annotation: LysR-family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 298 transmembrane" amino acids 226 to 246 (21 residues), see Phobius details PF00126: HTH_1" amino acids 5 to 63 (59 residues), 65.5 bits, see alignment E=3.3e-22 PF03466: LysR_substrate" amino acids 92 to 291 (200 residues), 151.4 bits, see alignment E=2.3e-48

Best Hits

Swiss-Prot: 33% identical to NOCR_AGRT7: Regulatory protein NocR (nocR) from Agrobacterium tumefaciens (strain T37)

KEGG orthology group: None (inferred from 100% identity to ccs:CCNA_01693)

Predicted SEED Role

"Transcriptional regulator, LysR family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C8P9 at UniProt or InterPro

Protein Sequence (298 amino acids)

>CCNA_01693 LysR-family transcriptional regulator (Caulobacter crescentus NA1000 Δfur)
MKLNLRSLEAFRETMLSGSATAAAGRMGLTQPAVSRLIAQLEQEVGFELFYRERGRLSPT
PEALIIYDEIDLAFGGLERVDALARDIAAFNTGLLKIVAPPSLSESVLSTILPRFMARFP
KVRIAIESRSTATARAMVANRTVDCGFVKLPLDRSDISTVTLSTSETVCVLPDTHPLTAH
EVLTPELLRGEPLVLLGAGTWTRRQIDDAFRERGVRPDVRVETHTVGSACALAAGGLGVA
IVNALLADNFARPGVAIRVFRPQILHEYAFMTSALAPMNRLAAAFLEEAQTFFREQAR