Protein Info for CCNA_01609 in Caulobacter crescentus NA1000 Δfur

Annotation: alkyl sulfatase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 651 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details PF00753: Lactamase_B" amino acids 118 to 343 (226 residues), 78.3 bits, see alignment E=1.6e-25 PF12706: Lactamase_B_2" amino acids 133 to 209 (77 residues), 29.3 bits, see alignment E=1.3e-10 PF14863: Alkyl_sulf_dimr" amino acids 380 to 518 (139 residues), 198.1 bits, see alignment E=1.6e-62 PF14864: Alkyl_sulf_C" amino acids 528 to 648 (121 residues), 112.4 bits, see alignment E=3.3e-36

Best Hits

Swiss-Prot: 47% identical to YJCS_ECOLI: Putative alkyl/aryl-sulfatase YjcS (yjcS) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 100% identity to ccs:CCNA_01609)

MetaCyc: 47% identical to linear primary-alkylsulfatase (Escherichia coli K-12 substr. MG1655)
RXN-15761 [EC: 3.1.6.21]

Predicted SEED Role

"alkyl sulfatase (EC 3.1.6.-)" (EC 3.1.6.-)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.6.- or 3.1.6.21

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C9V8 at UniProt or InterPro

Protein Sequence (651 amino acids)

>CCNA_01609 alkyl sulfatase (Caulobacter crescentus NA1000 Δfur)
MRKGMFAVSVLALILAAGAARAGEPATPTTAERQKAFAQTLPLNDRQDFEFADKGFLGTR
ADPIIRRADGQAAWNLAAYDFLKAEPPATVNPSLWRQAQLLSKHGLYQVSDRVYQVRGFD
ISNITFVRGDTGWIVIDPLTMQETARAALELVNEKLGKLPVTAVVYTHSHSDHFGGVRGV
VDEADVKSGKVPIVAPKGFMEEVAAENILAGNAMSRRAQYQFGVMLPPGVEGQITAGIGQ
NIARGSITLIPPTVIIDHTGQELTLDGVKVRFQYTPSTEAPAEMNLYFPDLRILDMAENA
NVSMHNILTPRGALVRDAKAWADGLTEALRLFGDNSDIMITSHGWPRFGGAVVKDFLADH
RDAYKYLHDQTVRMMNRGMTGDEIAAKIQLPPALARNWFNRGYYGSMSFNSRAVYQRYMG
WYDANPAHLIPAPPADSGKRYVAAMGGAAKVKALAGEAAAKGDYGWAASLLNHAVMADDG
DKEAKRLLAGVYDQLGYQTENALWRNMYLTAADELRGGVRKLPPSMTPLDMIAALESQMI
FDVLAIRLNAEKAGDARLRMVFAFPDRNERFLVEVRNGVLVAQPSKGGEGADATLTVDRA
VFLESLFGGTSLLPKILKGEVKLEGDRAAMSRLAGWFDTFPSDFPIVTRPN