Protein Info for CCNA_01572 in Caulobacter crescentus NA1000 Δfur

Annotation: major intrinsic protein (MIP)-family channel protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 224 signal peptide" amino acids 9 to 11 (3 residues), see Phobius details transmembrane" amino acids 12 to 30 (19 residues), see Phobius details amino acids 41 to 62 (22 residues), see Phobius details amino acids 85 to 107 (23 residues), see Phobius details amino acids 128 to 145 (18 residues), see Phobius details amino acids 157 to 178 (22 residues), see Phobius details amino acids 196 to 218 (23 residues), see Phobius details PF00230: MIP" amino acids 7 to 167 (161 residues), 83.4 bits, see alignment E=1.1e-27

Best Hits

KEGG orthology group: None (inferred from 100% identity to ccs:CCNA_01572)

MetaCyc: 58% identical to aquaglyceroporin (Sinorhizobium meliloti)
TRANS-RXN0-551

Predicted SEED Role

"Aquaporin Z"

MetaCyc Pathways

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C8F3 at UniProt or InterPro

Protein Sequence (224 amino acids)

>CCNA_01572 major intrinsic protein (MIP)-family channel protein (Caulobacter crescentus NA1000 Δfur)
MSPFDTPRRLVAEALGTALLLAVVVGSGIMGERLSDGNIAIALLGNTLATGAALVVLIWV
FGPISGAHFNPAVTLVAALRRELPLTLALAYPLAQILGGIAGVWTAHAMFGEPILQVSTK
LRSGGDQAFAEVVATFGLLATILGVSRFRPESTPMAVGLYITAAYWFTASTSFANPAVTV
ARSLSDSFAGIAPASAPAFILAQLVGALSAAALFGWLLKTDTSR