Protein Info for CCNA_01504 in Caulobacter crescentus NA1000 Δfur

Annotation: ATP-dependent DNA helicase recG

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 698 signal peptide" amino acids 1 to 19 (19 residues), see Phobius details PF04851: ResIII" amino acids 265 to 429 (165 residues), 31.5 bits, see alignment E=3.1e-11 PF00270: DEAD" amino acids 269 to 435 (167 residues), 77 bits, see alignment E=3e-25 PF00271: Helicase_C" amino acids 514 to 583 (70 residues), 61.4 bits, see alignment E=1.9e-20 PF19833: RecG_dom3_C" amino acids 613 to 686 (74 residues), 32.1 bits, see alignment E=2.1e-11

Best Hits

KEGG orthology group: K03655, ATP-dependent DNA helicase RecG [EC: 3.6.4.12] (inferred from 100% identity to ccs:CCNA_01504)

Predicted SEED Role

"ATP-dependent DNA helicase RecG (EC 3.6.1.-)" in subsystem DNA-replication (EC 3.6.1.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.6.1.-, 3.6.4.12

Use Curated BLAST to search for 3.6.1.- or 3.6.4.12

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C9J8 at UniProt or InterPro

Protein Sequence (698 amino acids)

>CCNA_01504 ATP-dependent DNA helicase recG (Caulobacter crescentus NA1000 Δfur)
MRPEILFPLFTSVSTLKGVGPRVAPLVEKLAGPIVRDVLFTAPSGLIRRTTTTVDQAVEN
QVQTFIVTIDGHQPPHRLGQPWKIRAWDGTGFLTLVWFKGHGPHLERQHPKGARRAVSGK
VERPEVFASELQIAHPDYIVAEDKAGDIPLVETVYPATHGLPSRTFRKLALEALARAPDL
AEWQDAAWIEREKLPSWRDALAALHAPASEADLSPLSRPRRRLAYDELLAHQLALAQRKA
ARRSHPGPRIPAGPLSEAAEKALPFKLTRAQIRALSEIRGDLASGERMSRLLQGDVGSGK
TVVAMLAMADAASAGFQSALMAPTEILARQHFETIAAPLEALDLSVILLTGRDKGAGRAA
KLAGLAEGAHHIAVGTHALFQDDVGFRALALTIIDEQHRFGVNERRRLQEKGPANVDWGV
HLLAMSATPIPRTLELTVFGDLDVSRIDEKPPGRTPVATRAVPTPRVPEIIERLRVAISG
GAQAFWICPLVSESDKVYLRAAEDRAADLARHLPGVGLVHGQMPPAEKDAVMQRFVDGEV
NVLVATTVVEVGVNVPNASIMVIEHADRFGLAQLHQLRGRVGRGTRESACVLLYDPPLSE
VAQQRLDILRRSDDGFEIAEKDLELRGGGDPLGLKQSGFPAYRLADPVAHRDLIAVAADD
ARLILARDLALTSPRGQALRTLQELFDWTPTSVLNEAG