Protein Info for CCNA_01467 in Caulobacter crescentus NA1000 Δfur

Annotation: cytochrome cbb3 oxidase subunit I ccoN

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 548 transmembrane" amino acids 12 to 35 (24 residues), see Phobius details amino acids 43 to 64 (22 residues), see Phobius details amino acids 84 to 107 (24 residues), see Phobius details amino acids 127 to 149 (23 residues), see Phobius details amino acids 161 to 184 (24 residues), see Phobius details amino acids 200 to 218 (19 residues), see Phobius details amino acids 230 to 252 (23 residues), see Phobius details amino acids 274 to 295 (22 residues), see Phobius details amino acids 306 to 324 (19 residues), see Phobius details amino acids 343 to 364 (22 residues), see Phobius details amino acids 376 to 399 (24 residues), see Phobius details amino acids 420 to 440 (21 residues), see Phobius details amino acids 452 to 472 (21 residues), see Phobius details amino acids 505 to 526 (22 residues), see Phobius details TIGR00780: cytochrome c oxidase, cbb3-type, subunit I" amino acids 74 to 544 (471 residues), 748.5 bits, see alignment E=1.7e-229 PF00115: COX1" amino acids 79 to 513 (435 residues), 383.3 bits, see alignment E=7.9e-119

Best Hits

Swiss-Prot: 66% identical to FIXN_BRADU: Cytochrome c oxidase subunit 1 homolog, bacteroid (fixN) from Bradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110)

KEGG orthology group: K00404, cb-type cytochrome c oxidase subunit I [EC: 1.9.3.1] (inferred from 100% identity to ccr:CC_1401)

MetaCyc: 70% identical to cytochrome cbb3 oxidase subunit I (Rhodobacter capsulatus)
CYTOCHROME-C-OXIDASE-RXN [EC: 7.1.1.9]

Predicted SEED Role

"Cytochrome c oxidase subunit CcoN (EC 1.9.3.1)" in subsystem Terminal cytochrome C oxidases (EC 1.9.3.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.9.3.1

Use Curated BLAST to search for 1.9.3.1 or 7.1.1.9

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C9F7 at UniProt or InterPro

Protein Sequence (548 amino acids)

>CCNA_01467 cytochrome cbb3 oxidase subunit I ccoN (Caulobacter crescentus NA1000 Δfur)
MSATTLRSAGPPAGSGALLAISVVGAFLAIFGAGLTHDPMFRLQIGTFALAGVIAAFALN
AGLAGGTLQDHPDEYSDNVVKAGVIATMFWGAAGLLVGVIIAAQLSWPTIFYFPDLGFLN
FGRLRPLHTSAVIFAFGGNALIATSFYVVQRTCKARLAGGITPWFVFWGYQLFIVLAATG
YLMGATSGKEYSEPEWYTDLWLTIVWVAYLLVFLGTIWKRKEPHIYVANWFYLAFIVTVA
LLHVVNNAAVPVGLLNHKSYGVFAGVQDALVQWWYGHNAVGFFLTAGFLAMMYYFVPRRV
ERPVYSYRLSIVHFWALIFIYIWAGPHHLHYTALPQWAQTLGMTFSIMLWMPSWGGMING
LMTLSGAWDKLRTDPVVRMMVVSIAFYGMSTFEGPVMSIRAVNALSHYTDWTIGHVHSGA
LGWVGFISFGAIYCLVPWLWKKPGMYSNKLIEWHFWIATTGILLYIAAMWVSGVMEGLMW
REYTPQGFLAYSFIETVSAKHIENVIRTVGGLMYLSGALIMIVNMWKTIASPSAAPADAS
AAPATAIA