Protein Info for CCNA_01420 in Caulobacter crescentus NA1000 Δfur

Annotation: NrdR family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 157 TIGR00244: transcriptional regulator NrdR" amino acids 1 to 144 (144 residues), 174.8 bits, see alignment E=5.8e-56 PF03477: ATP-cone" amino acids 50 to 136 (87 residues), 75.5 bits, see alignment E=2e-25

Best Hits

Swiss-Prot: 100% identical to NRDR_CAUVC: Transcriptional repressor NrdR (nrdR) from Caulobacter vibrioides (strain ATCC 19089 / CB15)

KEGG orthology group: K07738, transcriptional repressor NrdR (inferred from 100% identity to ccr:CC_1358)

Predicted SEED Role

"Ribonucleotide reductase transcriptional regulator NrdR" in subsystem Ribonucleotide reduction

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B8H533 at UniProt or InterPro

Protein Sequence (157 amino acids)

>CCNA_01420 NrdR family transcriptional regulator (Caulobacter crescentus NA1000 Δfur)
MRCPFCGHAESQVKDSRPSEDGAAIRRRRMCPECGGRFTTFERVQLRELIIVKRSGRRSP
FDRDKLVRSVGLATQKRPVDPERVERMVNGIVRQLESMGETELPSSTVGEMVMKALKSLD
DVAYVRYASVYRDFKETSDFAKFLTEEGLSDGGEEEL