Protein Info for CCNA_01243 in Caulobacter crescentus NA1000 Δfur

Annotation: ATP-dependent helicase hrpB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 823 TIGR01970: ATP-dependent helicase HrpB" amino acids 12 to 822 (811 residues), 1250.5 bits, see alignment E=0 PF00270: DEAD" amino acids 24 to 169 (146 residues), 39.1 bits, see alignment E=9.8e-14 PF00271: Helicase_C" amino acids 216 to 337 (122 residues), 47 bits, see alignment E=4.4e-16 PF08482: HrpB_C" amino acids 677 to 809 (133 residues), 165.1 bits, see alignment E=1.7e-52

Best Hits

KEGG orthology group: K03579, ATP-dependent helicase HrpB [EC: 3.6.4.13] (inferred from 100% identity to ccs:CCNA_01243)

Predicted SEED Role

"ATP-dependent helicase HrpB"

Isozymes

Compare fitness of predicted isozymes for: 3.6.4.13

Use Curated BLAST to search for 3.6.4.13

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C8Z1 at UniProt or InterPro

Protein Sequence (823 amino acids)

>CCNA_01243 ATP-dependent helicase hrpB (Caulobacter crescentus NA1000 Δfur)
MRFQGLCLHPMLPIENVLPALKAALLANNATVLVAPPGAGKTTAVPLALLDAPWVEGRKI
IVLEPRRLAARAAAARMASNLGESVGDTVGFRVRLQSKVSARTRIEVVTEGVFTRMILDD
PGLDGVAAVLFDEFHERSLDADLGLAFARDVQSVLREDLRLLIMSATLDGARISSLLNDA
PVVESQGRMFPVDTRYLGRDERQRLEERVGRAVERALAEESGSILVFLPGQGEIRRAESW
LNERLRRSDVDIAPLYGALEPAAQDRAISPAPAGRRKVVLATSIAETSLTIEGVRVVIDA
GQARVPRFDPASGITRLETVRVSRAAADQRRGRAGRTEPGVCYRLWDEPETRSLPAFARP
EILEADLSRLALDLARWGTKDPSDLTFLDPPPAAAFAEARTLLMRVQALDAQGDLTAHGK
ALADLPLPPRLAHMVARGAASGQAREAAEIAAVLTEQGLGGRDVDLRRRLEGLHRDRSPR
GRDAMALVERWSRAAGRSSGAKPLEIGLLLAEAYPERVAKARGKPGEFQLAGGRGVYLEP
TDPLAREAWLAVGELGGGDSRDRILLAAAVDEAQLRETFADRLVAEDRLETTGGKVRAKR
LLRLGKLVLEERLIENPDPAMIAGALLDQVRADGLSALRLGERGRALLDRVAFLRDVDGE
AWPDLSESALIERLDEWLEPLLAGRSSLSSLDEGTLYDALKTLVPWDLQRKMDALLPARF
EAPTGNSFAIDYSAEGGPRVEVRVGELYGLSEHPSVAGGKVPLTLSLLSPAHRPIQITKD
LPGFWKGSWREVKVEMKGRYPRHVWPDDPAAAAPVTRAKPRGT