Protein Info for CCNA_01220 in Caulobacter crescentus NA1000 Δfur

Annotation: 7-keto-8-aminopelargonate synthetase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 404 transmembrane" amino acids 270 to 288 (19 residues), see Phobius details amino acids 308 to 331 (24 residues), see Phobius details amino acids 338 to 355 (18 residues), see Phobius details PF00155: Aminotran_1_2" amino acids 45 to 384 (340 residues), 187.1 bits, see alignment E=1.1e-58 PF01212: Beta_elim_lyase" amino acids 89 to 318 (230 residues), 39.9 bits, see alignment E=6.4e-14

Best Hits

Swiss-Prot: 41% identical to BIOF_GEOMG: 8-amino-7-oxononanoate synthase (bioF) from Geobacter metallireducens (strain GS-15 / ATCC 53774 / DSM 7210)

KEGG orthology group: None (inferred from 100% identity to ccr:CC_1162)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C7E9 at UniProt or InterPro

Protein Sequence (404 amino acids)

>CCNA_01220 7-keto-8-aminopelargonate synthetase (Caulobacter crescentus NA1000 Δfur)
MGLFDKHLAYRDAYKAIQDVGANPFKVRFDAVHSPTEGVVDGRPTILLGTNNYLGLTFDE
QAIAASVKAVQERGTGTTGSRIANGSFESHVELEQELAKFYGRKHAMVFTTGYQANLGVL
STLVGRGDHLILDADSHASIYDGSRLGHAEVIRFRHNDPEDLAKRLRRLGDAPGERLIVV
EGIYSMIGDVAPLKEIAAVKREMGGYLLVDEAHSMGVLGATGRGLAEAAGVEEDVDFIVG
TFSKSLGAIGGFCVSDHDDFDVMRVICRPYMFTASLPPAVAASTVTALRRMIEQPELRDR
LNRNAKRLYDGLTAMGFLTGPSASPIVAATMPDQERAIAMWNGLLQAGVYLNLALPPATP
DSRPLLRASVSAAHTDEQIDAVLKTYGEIGAALGVIEPLKRARA