Protein Info for CCNA_01162 in Caulobacter crescentus NA1000 Δfur

Annotation: beta-D-glucoside glucohydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 767 signal peptide" amino acids 1 to 38 (38 residues), see Phobius details PF00933: Glyco_hydro_3" amino acids 51 to 368 (318 residues), 228.4 bits, see alignment E=2.2e-71 PF01915: Glyco_hydro_3_C" amino acids 409 to 645 (237 residues), 181.3 bits, see alignment E=3.5e-57 PF14310: Fn3-like" amino acids 682 to 750 (69 residues), 84.8 bits, see alignment E=5.5e-28

Best Hits

KEGG orthology group: K05349, beta-glucosidase [EC: 3.2.1.21] (inferred from 100% identity to ccs:CCNA_01162)

Predicted SEED Role

"Beta-glucosidase (EC 3.2.1.21)" in subsystem Beta-Glucoside Metabolism or Fructooligosaccharides(FOS) and Raffinose Utilization (EC 3.2.1.21)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.21

Use Curated BLAST to search for 3.2.1.21

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C5R6 at UniProt or InterPro

Protein Sequence (767 amino acids)

>CCNA_01162 beta-D-glucoside glucohydrolase (Caulobacter crescentus NA1000 Δfur)
MVLKTKTGGPVGSSRRGFLSGAAALAGLAVTAPPAFARASGRIEALLAQMTLEEKAGQLS
CFADMIRPPIGDINPLVNIRNAQTLIAEIKAGRIGTLINGVGAQAALDTQKAAVEGSRLK
IPLLFAADVIHGFRTVYPISLAEAASFDPHLAERTARAAAVEASASGLHWTFAPMVDVAR
DQRWGRVAEGSGEDVYLGEVMAAARVRGFQGRDLRAEDSMLATPKHFAGYGAVMAGMEYN
SVEMSEATLRETHLPPFQASFAAGAMTTMSAFNDINGIPATANRRLLTDILRGEWGFKGV
VISDYTADQELVAHGYAADDRDAARLAILAGIDISMQSGLYNRYLPELVTSGAVPVEAVD
QAVRRVLALKEAIGLFDNPYRSLDPEVERKHTATLAMRALSRESGARSIVLLKNDQGLLP
LPKAGKRLALIGPFADDRDNVLGAWGGFFADRRLNVDLATGLRAQMADPANLIVERGCEV
ETTIAGGFERAVAAAQAADIVLLAVGESEDMTGEAKSRTDIRIPPVQQRLAEAIAATGKP
VVVLLRHGRAIALEGVVKDAPAILATWFLGSEMGHAVADVLFGAVNPSGRLPVSFPIDSG
QQPFFYNSRTTGRPAPADPNAQEYKARWRSIRNDALYPFGFGLGYTSFSLSDLKLSTARL
AWDDTLHVTAKVRNTGQVHGDHVVQLYIRDRVASRTRPVRELKGFQRVSLAPGAEREVHF
ELRRENLMFVGDNDYWTVEPGAFDVWVANSCVDGLMGSFELLPFDRG