Protein Info for CCNA_01100 in Caulobacter crescentus NA1000 Δfur

Annotation: acylamino-acid-releasing enzyme

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 642 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details PF05448: AXE1" amino acids 383 to 598 (216 residues), 21.1 bits, see alignment E=6.8e-08 PF02129: Peptidase_S15" amino acids 389 to 526 (138 residues), 32.1 bits, see alignment E=5.5e-11 PF00756: Esterase" amino acids 392 to 601 (210 residues), 30.6 bits, see alignment E=1.6e-10 PF20434: BD-FAE" amino acids 399 to 599 (201 residues), 36.2 bits, see alignment E=2.6e-12 PF12697: Abhydrolase_6" amino acids 411 to 617 (207 residues), 30.1 bits, see alignment E=4.4e-10 PF00326: Peptidase_S9" amino acids 425 to 638 (214 residues), 147.6 bits, see alignment E=2.1e-46 PF01738: DLH" amino acids 427 to 616 (190 residues), 29.1 bits, see alignment E=4.2e-10 PF07859: Abhydrolase_3" amino acids 479 to 616 (138 residues), 26 bits, see alignment E=4.2e-09

Best Hits

KEGG orthology group: None (inferred from 100% identity to ccs:CCNA_01100)

Predicted SEED Role

"prolyl oligopeptidase family protein" in subsystem Synechocystis experimental

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C6H0 at UniProt or InterPro

Protein Sequence (642 amino acids)

>CCNA_01100 acylamino-acid-releasing enzyme (Caulobacter crescentus NA1000 Δfur)
MFKLFAAAIAALFLVGAASAAEKPDLAIYGRLPRIEGATISPDGSKLALIVTDGEERALV
LRTREGELLGGVKAAKTKLRDVIWAGEDHVIMISSQTAEVFGLRGPAREYLMAVDYNLTT
RKQSLLLRGQKDSMNVVLDHPMIRMINGQPVAFVEGVHFLPDYGVNMLFRVSLKDGHTRM
LDFGARDDVNSWLVNAAGEPVAQSLYDSEKGRWALRMRIGSSWKIVDEADAPMGSFGLYG
FGRDGKSVLVWRGDDKGVSILREYRGVGQYEDLPEDLDLSGLLHDPDSLALLGGYTLKGD
DLVYTFFDPASQKTWNSVAKAFEGDRVSLQSWSKNRRQVVVLVDSATSGPAYALVDLDAK
NATWLGDVYGGLTKAAISPVRPIRYKAADGLEISGYLTLPKGRDPKNLPLIVLPHGGPEG
RDTPGFDWWSQALASRGYAVLQPNFRGSEGFGWDFVKAGFGEWGKKMQTDLSDGVRDLVK
QGIVDPKRVCIVGASYGGYAALAGATLDPGVYRCAVSVAGPSDLRKMLLSVREANNGDMS
AAQRYWLRFMGADGIKDPDLIAISPAKLADRVEIPIMLIHGKDDTVVRYDQSVAMADALR
KAGKPVEFVTLNGEDHWLSSGATRLKMLTEAVAFVEKHNPPD