Protein Info for CCNA_01099 in Caulobacter crescentus NA1000 Δfur

Annotation: tetracycline resistance protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 396 transmembrane" amino acids 12 to 35 (24 residues), see Phobius details amino acids 46 to 64 (19 residues), see Phobius details amino acids 76 to 95 (20 residues), see Phobius details amino acids 100 to 122 (23 residues), see Phobius details amino acids 134 to 155 (22 residues), see Phobius details amino acids 166 to 186 (21 residues), see Phobius details amino acids 218 to 239 (22 residues), see Phobius details amino acids 246 to 269 (24 residues), see Phobius details amino acids 281 to 300 (20 residues), see Phobius details amino acids 306 to 328 (23 residues), see Phobius details amino acids 341 to 363 (23 residues), see Phobius details amino acids 371 to 389 (19 residues), see Phobius details PF13347: MFS_2" amino acids 5 to 114 (110 residues), 35.9 bits, see alignment E=8.1e-13 amino acids 138 to 326 (189 residues), 30.3 bits, see alignment E=4.1e-11 PF06779: MFS_4" amino acids 6 to 179 (174 residues), 30.7 bits, see alignment E=5.5e-11 PF07690: MFS_1" amino acids 14 to 356 (343 residues), 183.9 bits, see alignment E=1e-57 amino acids 244 to 391 (148 residues), 56.3 bits, see alignment E=6.9e-19 PF12832: MFS_1_like" amino acids 19 to 363 (345 residues), 56.2 bits, see alignment E=7.9e-19 PF00083: Sugar_tr" amino acids 44 to 189 (146 residues), 55.5 bits, see alignment E=1.2e-18

Best Hits

KEGG orthology group: None (inferred from 100% identity to ccr:CC_1047)

Predicted SEED Role

"Major facilitator superfamily MFS_1"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C5J3 at UniProt or InterPro

Protein Sequence (396 amino acids)

>CCNA_01099 tetracycline resistance protein (Caulobacter crescentus NA1000 Δfur)
MSEPAHSNRALAVLLLVVFINLVGFGVIIPLLPFYARSMDAAPRQVTTMFAAYSLGQFFG
EPFWGRLSDRIGRRPVLIVTIIANTLAYLALAFAPNIWVAMLIRLFGGFGSGNISTIQGY
MADVTPPEKRAGRMGLLGAAFGAGFVIGPGLVMVMQPGAGALGYQLPLFLAAAMAGTAAL
GVILFVKESRAPSAPGAPQAHRLEALSQAAAHPVLSRVLLVTLISTAAFAGMEAVFGLYA
DTRFGWTASQVAACFALIGVIASIGQGVLTGRLARRFGEARVLTAGLSIIATSLLITPFI
SKPALAVVAVAFTAFGQSLVFPCVGALISRATPPDRQGQMLGLNMAAGSLARIGGPLLAG
PLFGLAIGGPYWFGAALMVPAIGFALVIVRRTKVAA