Protein Info for CCNA_00815 in Caulobacter crescentus NA1000 Δfur

Annotation: lignostilbene-alpha,beta-dioxygenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 483 PF03055: RPE65" amino acids 26 to 476 (451 residues), 395.2 bits, see alignment E=2.7e-122

Best Hits

KEGG orthology group: K11159, carotenoid cleavage dioxygenase (inferred from 100% identity to ccs:CCNA_00815)

Predicted SEED Role

"Lignostilbene-alpha,beta-dioxygenase and related enzymes" in subsystem Phenylpropanoid compound degradation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C6L9 at UniProt or InterPro

Protein Sequence (483 amino acids)

>CCNA_00815 lignostilbene-alpha,beta-dioxygenase (Caulobacter crescentus NA1000 Δfur)
MKVERLPPVRTSLGPTNHPYMTGPWTPQHEEVNAWDLEVLEGAIPADLDGVYLRNTENPV
HDPIGRYHPFDGDGMIHQIEFKGGAATYRNRFVRTRCFEAEQEVNEGLWGGLMDGPGVSK
RPGFGAHGALKDSASTDIVVHNGEAIATFYQCGEAYRLDPLTLENLGVASWAPLEGVSAH
PKVDEATGELMFFNYSKAWPYMHYGVVGPDGKRKVYQGVPLPGPRLPHDMAFSSKYAILN
DLPVFWDQELMARDIHAVRLHKGIPSRFALVPREGGEPRWFEAEPTYVLHWLNAYEDGDE
VVLDGYFQEKPIPRPLEGAPDGHGHLMAYLDEHSFLPKLHRWRFNLKTGETTEKHLDDRV
LEFGMFNQKYAGKPYRYAYSTTAKPGWFLFNGFVKHDLETGESWSIALPEGRYASEAPFA
PKVGAVDEDDGYLVSFIIDENKGASECLIVDAKRFEVVCRIALPHKLSSGTHTVWAGREM
LTK