Protein Info for CCNA_00651 in Caulobacter crescentus NA1000 Δfur

Annotation: nitrite reductase (NAD(P)H) catalytic subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 822 PF07992: Pyr_redox_2" amino acids 9 to 286 (278 residues), 210.6 bits, see alignment E=1e-65 TIGR02374: nitrite reductase [NAD(P)H], large subunit" amino acids 10 to 801 (792 residues), 897.9 bits, see alignment E=3.6e-274 PF00070: Pyr_redox" amino acids 152 to 233 (82 residues), 59.2 bits, see alignment E=1.4e-19 PF18267: Rubredoxin_C" amino acids 322 to 388 (67 residues), 61.2 bits, see alignment E=2.2e-20 PF04324: Fer2_BFD" amino acids 427 to 475 (49 residues), 49.5 bits, see alignment 1.3e-16 amino acids 491 to 540 (50 residues), 46.9 bits, see alignment 8.7e-16 PF03460: NIR_SIR_ferr" amino acids 566 to 630 (65 residues), 58 bits, see alignment E=2e-19 PF01077: NIR_SIR" amino acids 639 to 776 (138 residues), 108.2 bits, see alignment E=8.9e-35

Best Hits

KEGG orthology group: K00362, nitrite reductase (NAD(P)H) large subunit [EC: 1.7.1.4] (inferred from 100% identity to ccr:CC_0615)

Predicted SEED Role

"Nitrite reductase [NAD(P)H] large subunit (EC 1.7.1.4)" in subsystem Nitrate and nitrite ammonification (EC 1.7.1.4)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.7.1.4

Use Curated BLAST to search for 1.7.1.4

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C6A5 at UniProt or InterPro

Protein Sequence (822 amino acids)

>CCNA_00651 nitrite reductase (NAD(P)H) catalytic subunit (Caulobacter crescentus NA1000 Δfur)
MTQATPKLRLVVIGNGMAGCRAVEEVLKRDPDRYAVTIFGAEPRVNYNRIMLSPVLAGEK
AFEDIVINDEAWYRDNGITLHAGRAVTAIDLAARKVFAEGGLEIGYDKLILATGSDPFRL
PLPGGDLKGVVTFRDLDDVNAMLAASAEPDARAVVIGGGLLGLEAAYGLARRGMAATVVH
LMDVLMERQLDESAGYLLREALADRGVETVLGAHSEEIVGADGQVTGLKLKDGRVLPCDL
LVMAVGIRPNTTLAKAAGLTVNRGVAVDDAMRTSDPDVFAVGECVEHRGQCYGLVAPIWE
MCRALAQALTDGEGAYQGSVLSTRLKVSGVDVFSAGKFAGGEGCEDIVFRDAARGVYKRV
VIEDGKVAGAVLFGDAADGGWYFDLMKAGADVAGIRETLIFGQAITEGLSGLDPSAAVAA
MPDTQEICGCNGVCKGAITSAITAQGLTTLDDVRAVTKASASCGSCTPLVEQVLKLTLGD
GFQAQTGPKPICKCSPKTHGDVRRAIVDQGLKSMPAVMQALEWSTPDGCASCRPALNYYL
LCAWPGEYRDDKQSRYINERVHANIQKDGTYSVVPRMWGGMTSPAELRAIADVAEKFAIP
AVKVTGGQRIDLLGVKKDDLPAVWADLNAAGMVSGHAYAKGLRTVKTCVGSDWCRFGTQD
STGLGMRLEKFLWGSWAPAKVKLAVSGCPRNCAEATCKDFGVVCVDSGYEIHIGGAAGLH
IQGTQVLTRVATEDEAVWVIAAAMQLYREEGWYLERVYKWMDRVGLESIRAQVTDPDQRR
ALYDRFVYSQRFARIDPWAERVAGRHNEEFTPMSRRMEFVPA