Protein Info for CCNA_00456 in Caulobacter crescentus NA1000 Δfur

Annotation: beta-N-acetylhexosaminidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 757 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details PF02838: Glyco_hydro_20b" amino acids 30 to 154 (125 residues), 72.4 bits, see alignment E=1.2e-23 PF00728: Glyco_hydro_20" amino acids 157 to 494 (338 residues), 419.4 bits, see alignment E=2.8e-129 PF13290: CHB_HEX_C_1" amino acids 539 to 590 (52 residues), 45.1 bits, see alignment 1.7e-15 PF13287: Fn3_assoc" amino acids 543 to 589 (47 residues), 35.3 bits, see alignment 2.1e-12

Best Hits

KEGG orthology group: K12373, hexosaminidase [EC: 3.2.1.52] (inferred from 100% identity to ccs:CCNA_00456)

Predicted SEED Role

"Beta-hexosaminidase (EC 3.2.1.52)" in subsystem Chitin and N-acetylglucosamine utilization or N-Acetyl-Galactosamine and Galactosamine Utilization (EC 3.2.1.52)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.52

Use Curated BLAST to search for 3.2.1.52

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C3S4 at UniProt or InterPro

Protein Sequence (757 amino acids)

>CCNA_00456 beta-N-acetylhexosaminidase (Caulobacter crescentus NA1000 Δfur)
MTLTPLRIVAVSTFALTAALATGAFADSLTITPAPAKVVRAEGTFTLSASTRIHVARGDI
EAKGVALQLADLIQRSRGFRPKVVEGPPAADAIVLTREGPAGEAYKLDINAKGATIAAAK
RAGLFYGAMSLWQLATPDEAKGPVALLAASIEDAPRFAWRGLMVDSARHYQSLDTLKAVI
DAMAAHKLNTFHWHLVDDQGWRLEIKKYPKLTQVAAWRRNPGAAVNYPKYGGFYTQDQAR
ELVAYAAARNITVVPEIETPGHALAPIVAYPQLGTAPPDASKMGDWGIFPWLYNTDDATF
AFLDDVLNEVMDIFPSTFIHVGGDEAIKDQWKASPKVQAKIKELGLKDEHELQSWFIQRV
GKSLEKRGRRLIGWDEILEGGLAPNATVMSWRGIDGAIAAAKQGHDTVLSPHPVLYLDHR
QSASAEEPTGRGHISSLKDVYAFDPAPVQLTPDERKHILGVQANVWTEHMQTDQRMQLMA
FPRAVALAERAWSPEASADWDGFAKRLPAEMARLKVLGVAANPVPFEPQPALSEAEGGKT
RVALSTGLGVGQIRYTTDGKAPTATSSTYAGPIELPTGAVLKAQTFVEGQPLGRERSWTM
SADLLQTRTSGQLKLCTQQVPLTMIDDAPAALDQRPMMMVDIFNPCWIWEGARLDKGAML
SARVTQIPFNFQVGKDRDKIPLHPPATPGGELEVRLGCSGERIAAIPLGDAARNPGLSTI
TGRLPARAEKADLCLTFTSRSLDPFWVVERMTLKPAN