Protein Info for CCNA_00373 in Caulobacter crescentus NA1000 Δfur

Annotation: ATP synthase A chain

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 253 transmembrane" amino acids 31 to 52 (22 residues), see Phobius details amino acids 88 to 111 (24 residues), see Phobius details amino acids 117 to 137 (21 residues), see Phobius details amino acids 156 to 180 (25 residues), see Phobius details amino acids 189 to 216 (28 residues), see Phobius details amino acids 218 to 245 (28 residues), see Phobius details TIGR01131: ATP synthase F0, A subunit" amino acids 5 to 247 (243 residues), 196.9 bits, see alignment E=2.3e-62 PF00119: ATP-synt_A" amino acids 38 to 245 (208 residues), 206.4 bits, see alignment E=2.7e-65

Best Hits

Swiss-Prot: 56% identical to ATP6_HYPNA: ATP synthase subunit a (atpB) from Hyphomonas neptunium (strain ATCC 15444)

KEGG orthology group: K02108, F-type H+-transporting ATPase subunit a [EC: 3.6.3.14] (inferred from 100% identity to ccs:CCNA_00373)

Predicted SEED Role

"ATP synthase F0 sector subunit a (EC 3.6.3.14)" (EC 3.6.3.14)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.14

Use Curated BLAST to search for 3.6.3.14

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C557 at UniProt or InterPro

Protein Sequence (253 amino acids)

>CCNA_00373 ATP synthase A chain (Caulobacter crescentus NA1000 Δfur)
MADPMHQFQIQKIVELPTVTVPGLGAIDLSITNSVAAMMSAALLIIGFYALSAKKAVVPG
RLQSVGEMLYGLVDGLAESIIGHDGKKFLPFIFTLFAFVLFMNVQGMFLVFTATSQLAVT
LTLGLMVILTVVAVGFAKNGLKFFKLFAPSGVPWPLYFLLVPIEILSFLIRPITLGLRLF
GNMLGGHVVLKIFAGFVVALGGLGVLGWAGAALALTSVVALTALEFMVAFLQAFVFAVLA
CVYINDVVHLDSH