Protein Info for CCNA_00247 in Caulobacter crescentus NA1000 Δfur

Annotation: two-component receiver protein SpdR

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 185 PF00072: Response_reg" amino acids 17 to 124 (108 residues), 80.7 bits, see alignment E=9.1e-27 PF02954: HTH_8" amino acids 148 to 177 (30 residues), 26.5 bits, see alignment 4.2e-10

Best Hits

Swiss-Prot: 68% identical to REGA_RHOCA: Photosynthetic apparatus regulatory protein RegA (regA) from Rhodobacter capsulatus

KEGG orthology group: K15012, two-component system, response regulator RegA (inferred from 100% identity to ccr:CC_0247)

Predicted SEED Role

"Dna binding response regulator PrrA (RegA)"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C6B9 at UniProt or InterPro

Protein Sequence (185 amino acids)

>CCNA_00247 two-component receiver protein SpdR (Caulobacter crescentus NA1000 Δfur)
MADIGELVAALPDKSLLLLDDDAPLRTRLGRALEQRGFEVTLAASVAEALTILRTQAPAH
AVLDMRLEDGSGLKVVEAVRDARADAKVIMLTGYGNIATAVAAVKAGVVDYLSKPADADD
VARALLAAKDAAPAPPENPMSADRVRWEHIQRVYEMCGHNVSETARRLNMHRRTLQRILA
KRAPR