Protein Info for CCNA_00063 in Caulobacter crescentus NA1000 Δfur

Annotation: MviN-family integral membrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 520 transmembrane" amino acids 20 to 38 (19 residues), see Phobius details amino acids 50 to 68 (19 residues), see Phobius details amino acids 88 to 110 (23 residues), see Phobius details amino acids 126 to 150 (25 residues), see Phobius details amino acids 157 to 177 (21 residues), see Phobius details amino acids 187 to 207 (21 residues), see Phobius details amino acids 228 to 250 (23 residues), see Phobius details amino acids 269 to 287 (19 residues), see Phobius details amino acids 308 to 331 (24 residues), see Phobius details amino acids 351 to 373 (23 residues), see Phobius details amino acids 384 to 402 (19 residues), see Phobius details amino acids 408 to 427 (20 residues), see Phobius details amino acids 439 to 462 (24 residues), see Phobius details amino acids 482 to 507 (26 residues), see Phobius details TIGR01695: murein biosynthesis integral membrane protein MurJ" amino acids 2 to 503 (502 residues), 375.8 bits, see alignment E=1.7e-116 PF03023: MurJ" amino acids 26 to 456 (431 residues), 322.7 bits, see alignment E=3.5e-100 PF01554: MatE" amino acids 274 to 396 (123 residues), 37.1 bits, see alignment E=2.6e-13

Best Hits

KEGG orthology group: K03980, virulence factor (inferred from 100% identity to ccs:CCNA_00063)

Predicted SEED Role

"Proposed peptidoglycan lipid II flippase MurJ" in subsystem ZZ gjo need homes

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C4E4 at UniProt or InterPro

Protein Sequence (520 amino acids)

>CCNA_00063 MviN-family integral membrane protein (Caulobacter crescentus NA1000 Δfur)
MIRSSAIYSGLTLVSRLMGFVRDLVISYFLGASANFAADAFNTAQMFPNLFRRIFAEGAF
AAAFVPAYSKTLDRDGAEVADKLAADAMATIAAFTVGLTLIAQATMPWLMMVISPGFGFG
TDKYKLAVILTQITMPYLPCMAIVALLSGVLNARGKFIVSAAAPILLNLVTLIAVIPTRN
AHDAALAASWGIFAAGIAQVALLVWAVRKAGATIRWRLPRLTPEIRGLIALAIPGAIAAS
ASQINITISGVLASHVNGARTWLAYADRLYQLPLGLVGVAIGVALLPRLSRAVAAEDRAE
AQGAMDQAIVFALALTLPAAVALFSIPFFLIDGLFTRGEFTVFDARQTANALLHYGWGTP
AFVLARILSPAFFARGDTKGPMRFALISVAVNIGLGLALFPVMGVPGLAAATSAASWINV
LQMALTLRKRGDYAPSAAAWGKIIRVLGASVALGLILAAISRGRAALEAPILAMGIGSAK
ELAILATCALAAGLYPVLLLLSGGVTLAEARTVLRRGTGR