Protein Info for CCNA_00052 in Caulobacter crescentus NA1000 Δfur

Annotation: metal-dependent hydrolase/metalloproteinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 151 PF02130: YbeY" amino acids 12 to 136 (125 residues), 118.3 bits, see alignment E=1e-38 TIGR00043: rRNA maturation RNase YbeY" amino acids 38 to 138 (101 residues), 114.6 bits, see alignment E=1.2e-37

Best Hits

Swiss-Prot: 99% identical to YBEY_CAUVN: Endoribonuclease YbeY (ybeY) from Caulobacter vibrioides (strain NA1000 / CB15N)

KEGG orthology group: K07042, probable rRNA maturation factor (inferred from 99% identity to ccr:CC_0054)

Predicted SEED Role

"Metal-dependent hydrolase YbeY, involved in rRNA and/or ribosome maturation and assembly"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B8GX09 at UniProt or InterPro

Protein Sequence (151 amino acids)

>CCNA_00052 metal-dependent hydrolase/metalloproteinase (Caulobacter crescentus NA1000 Δfur)
MEIEDEAWTTAEADAEALVWRAAQAVLDAHEDIEGQGIVILLTDDDSVQALNRDFRKKDY
ATNVLSFPSPPNPEGQIGDIALAYGVCAREAAEQGKPLAHHLQHLVAHGVLHLLGYDHER
DDEAEAMEALEREILAGLDVPDPYASDEEGR