Protein Info for CA264_21330 in Pontibacter actiniarum KMM 6156, DSM 19842

Annotation: MBL fold metallo-hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 451 PF00753: Lactamase_B" amino acids 11 to 175 (165 residues), 53 bits, see alignment E=4.4e-18 PF00581: Rhodanese" amino acids 267 to 314 (48 residues), 28.6 bits, see alignment 1.6e-10 amino acids 365 to 442 (78 residues), 35.9 bits, see alignment E=8.7e-13

Best Hits

KEGG orthology group: None (inferred from 52% identity to fte:Fluta_2869)

Predicted SEED Role

"Metallo-beta-lactamase family protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9YZ79 at UniProt or InterPro

Protein Sequence (451 amino acids)

>CA264_21330 MBL fold metallo-hydrolase (Pontibacter actiniarum KMM 6156, DSM 19842)
MYIERFYDEGLAHASYAVLSEKQVAFVDPARDPQPYLSFAERHGAKVVAVVETHLHADFV
SGHLEIRDIANAPVYVSQLAEATYPHTAFDQGDEITVGEIALKALNTPGHSPDSISILVL
DEQGREQAVFSGDTLFVGDVGRPDLREDSNDSRTRREDMARQLYHSTRQVLMQLDKDVKV
YPAHGAGSLCGKSISSELSSTIGQEAAHNYALQPMSEDAFVQVLLKEQPYIPKYFSHDVA
WNRRGAGAFKKCVEAVPRLNKYASLQQDVLLVDTRPEWQFKAGHLPGAINIMDGKEFETW
LGSLIGPEEEFYLLAENEEALEVLIRKAAKIGYEQNIKGALQVPTCGQQPSSKIDLGAFR
EHPQDFTIVDLRNESEVKKDEIFKDAVHIPLPELPGRASEIRKDKPVVVHCASGYRSAIG
ASILEKVVDAPVYDLGEAVKEFKQPIVKAAE