Protein Info for CA264_21055 in Pontibacter actiniarum KMM 6156, DSM 19842

Annotation: CusA/CzcA family heavy metal efflux RND transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1200 1300 1400 1469 signal peptide" amino acids 12 to 13 (2 residues), see Phobius details transmembrane" amino acids 14 to 31 (18 residues), see Phobius details amino acids 342 to 359 (18 residues), see Phobius details amino acids 365 to 385 (21 residues), see Phobius details amino acids 391 to 414 (24 residues), see Phobius details amino acids 447 to 466 (20 residues), see Phobius details amino acids 478 to 502 (25 residues), see Phobius details amino acids 546 to 564 (19 residues), see Phobius details amino acids 884 to 903 (20 residues), see Phobius details amino acids 910 to 929 (20 residues), see Phobius details amino acids 935 to 957 (23 residues), see Phobius details amino acids 984 to 1005 (22 residues), see Phobius details amino acids 1014 to 1040 (27 residues), see Phobius details amino acids 1052 to 1074 (23 residues), see Phobius details TIGR00914: heavy metal efflux pump, CzcA family" amino acids 1 to 1043 (1043 residues), 1140 bits, see alignment E=0 PF00873: ACR_tran" amino acids 5 to 1040 (1036 residues), 906.9 bits, see alignment E=1.6e-276 PF02321: OEP" amino acids 1094 to 1268 (175 residues), 39.3 bits, see alignment E=6.1e-14 amino acids 1294 to 1464 (171 residues), 60.2 bits, see alignment E=2.4e-20

Best Hits

Predicted SEED Role

"Cobalt-zinc-cadmium resistance protein CzcA; Cation efflux system protein CusA"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9YZ09 at UniProt or InterPro

Protein Sequence (1469 amino acids)

>CA264_21055 CusA/CzcA family heavy metal efflux RND transporter (Pontibacter actiniarum KMM 6156, DSM 19842)
MINSIIAFSIRNKLIIGLMIVAWIGAGVWAMSTVNLGSVPDITNNQVQVITTSENLSTED
IEQFVTYPVELTMANLPGVEEIRSISRFGLSVVTVVFDEGMGTYLPRQLVQEKLSEVEIP
EQFGEPSMGPISTGLGEIYQYVLEPQPGYDSVYTPTELRTIQDWIVARQMALVPGVVEVN
AFGGNIKQYEVALDPGKLNSMNVSISEVFEALEKNNVNTGGAYIERNSMANFIRGEGLVR
SLDDIRNIVVRNENGTPILIRDVADAVQFGSQVRYGAFTQDGREAVGGMVLMLRGESPDK
VINAVKERMAEVQKSLPEGLVIKPFIDQSNLIARTTSTVSKNLTEGALIVVFVLVLLLGS
LRGGLITASVIPLALLFAFILMRIFNVSANLMSLGAIDFGIIVDGAVIIVEGTVHMIEKR
MKEGKGNFGQQMDEIAYESSSTMMNSAFFGQIIILIVFAPILFLTGVEGKMFQPMAYTFG
FAVLGSIILCLTYVPVVSALFLKPSHGKKNLLSKFENKVEHVSNRLMGGVNKGYLPLLRK
SLNHKVVVLMSAVVLLVGAVLTFSRMGGEFIPSLDEGDIAMQALLRPGSSLSESIEQSKK
IEKIVLENFPEVKTMVARIGVSAIPTDPMPMDILDSFIILEKDMDKWESADSKEELIGKI
KEKLSVLPGINFVFSQPVELRFNELISGVREDVAVKLYGEDLNVLASKGQQMAQIIQTVP
GVGDVNLEAISGLPQMTVRFDRGKIAQYGLDIEKLNNYISAAFAGGVAGVVFEGERRFDI
AVRLSEVNRRSIEDLRNLYIDLPNGEQVPLQQVADISYQPGPMQISRDNTSRRINVGVNV
RGRDVESMVNEIQQKLDAQLNLPPGYYVTYGGSFENLQRAKARLQVVVPIALALIFILLY
FALKSLSQSIMIYMAVPLAAIGGIFALALRGMPFSISAGVGFIVLFGVAVLNGLVLVSRF
NSLKEEGITDLKQRIFIGTEERLRPILLTATAAIMGFIPMAFSASAGAEVQRPLATVVIG
GLITATFLTLVVVPILYFFVESKVGKSGGKGNMAMAPSLVIPLVIGAGLFFSPAAATAQD
KKALPDNMPAISMEEAVQRAVANYPSVTAARLGIENQQALKSTAWNLGSTQVFTGKEEVG
NESQGVQNRIGIQQQNIEVFSIAPRLNLQQKQVNLAQSALNLTSLEVAREVRIAWSNTYA
ARSQYLLYQRLDSIFSEFTRAAKVRYETEAISHLEYLAATNQARQITVQQEQAFRNYQAA
LRQLNQWLVNDTPLTAALTEPEQLTAPLPGIADTLSQHPLLDYSRQQVEVAQARLRVAKA
AYLPSLSGQYADQKIAGQSGFYSYQIGINFPLLPFAERGRAQSAKIEREIAEQNLRRTQL
ELQAGYGSLLEEYRKWLNSWQYYQQEALPLAVEQRNGAIIAYREGAIDYIGFLQIIRDAI
QVEFNAQEALGNYLDTKARLIYFLQSSNQ