Protein Info for CA264_20705 in Pontibacter actiniarum KMM 6156, DSM 19842
Annotation: N-acyl-L-amino acid amidohydrolase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 38% identical to YHAA_BACSU: Putative amidohydrolase YhaA (yhaA) from Bacillus subtilis (strain 168)
KEGG orthology group: None (inferred from 64% identity to sli:Slin_0207)MetaCyc: 38% identical to N-acetyl amino acid acetylase (Bacillus subtilis subtilis 168)
3.5.1.-
Predicted SEED Role
"N-acetyl-L,L-diaminopimelate deacetylase (EC 3.5.1.47)" in subsystem Lysine Biosynthesis DAP Pathway (EC 3.5.1.47)
MetaCyc Pathways
- L-lysine biosynthesis II (7/9 steps found)
- S-(2-succinyl)-L-cysteine degradation (2/4 steps found)
- S-benzyl-L-cysteine degradation (1/5 steps found)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 3.5.1.47
Use Curated BLAST to search for 3.5.1.47
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A1X9YXL5 at UniProt or InterPro
Protein Sequence (444 amino acids)
>CA264_20705 N-acyl-L-amino acid amidohydrolase (Pontibacter actiniarum KMM 6156, DSM 19842) MIRTYTLKQRAILAAAGFTLLSAPTIAQDTKLMAKASTLADKVEPQVIEWRRHFHEHPEL SNRETETAARIAAELKKMGIEVETGVAKHGVVGILKGGKPGPVVALRADIDGLPVTERAN IPFASKAKGTYNGNEVGVMHACGHDTHIAMLLGAAEVLSSMKNDLKGTVKFLFQPAEEGA PAGEEGGARLMVKEGVLEKGPKPEVIFGLHINSQTEVGTLKYRPGGIMAGADVFRIKVKG KQVHGANPWAGVDPIVVSSQIIYGLQTIISRQTELTEDAAVITVGMIHGGVRNNIIPEEV QMEGTIRTLDKEMQKKIHDKIRLTATNIAESAGATAEVEIEEMAAITYNEPALTEKMLPT LQATAGKGKVVLMNAMTGAEDFSYFQQEIPGLYLFVGGMPKGQNPAKAPAHHTPDFYVDE SGMKLGVKTLTNLTLDYMNGKGKR