Protein Info for CA264_20540 in Pontibacter actiniarum KMM 6156, DSM 19842

Annotation: transglycosylase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 776 transmembrane" amino acids 21 to 43 (23 residues), see Phobius details PF00912: Transgly" amino acids 74 to 259 (186 residues), 189 bits, see alignment E=5.4e-60 PF00905: Transpeptidase" amino acids 436 to 673 (238 residues), 90.4 bits, see alignment E=1.3e-29

Best Hits

KEGG orthology group: K05366, penicillin-binding protein 1A [EC: 2.4.1.- 3.4.-.-] (inferred from 57% identity to chu:CHU_3131)

Predicted SEED Role

"Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) (EC 3.4.-.-)" in subsystem Peptidoglycan Biosynthesis or Type IV pilus (EC 2.4.1.129, EC 3.4.-.-)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.4.1.-, 2.4.1.129, 3.4.-.-

Use Curated BLAST to search for 2.4.1.- or 2.4.1.129 or 3.4.-.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9YXT3 at UniProt or InterPro

Protein Sequence (776 amino acids)

>CA264_20540 transglycosylase (Pontibacter actiniarum KMM 6156, DSM 19842)
MPKEQEKVQEPKTTVFGKVVSFVWKVFFLGFAVVLLYLLSVEYNLLYLFGASPSLDRLEN
PRSDQASELYTADGQLIGKYFRENRSPVGYKDMSPQLIQALIATEDVRFYEHSGIDPHAI
VSAVYGSLQGDARGASTITQQLAKNLYKTRTDDSKGVLGHVPGINIVISKTKEWLTAIKL
EQRYTKEEILAMYLNTVDFGSNSFGIKVASSTFFNTSPDSLKVEQAAVLVGLLKAPTYYS
PRFNPKNATRRRNTVLGQMVKYGYLPQAEADSLSQLPLVLDYSVENHYDGPATYFRGAVA
DYLQEWCKENGYDLYRDGLRIYTTIDSRIQAHAEAAMEEQMRTLQRRFDNHWKGRNPWVD
EKDKEIPGFIEETIKRTAYYRRLQKKYGDDMAAIKRELNRPREMKVFTWDNDSLEKTVTM
SPLDSLAYYKHFLHGGMMTMDPFTGHIKAWVGGINFKYFKYDHVKQARRQPGSTFKPFVY
VSAIDNGYSPCDKLVDKRITINYVEKGEKKSWSPTNADWEYTGAPMTLRRGMGKSVNSVT
AQLTELVGWETVVAYAHKLGITSPLQAVPSIGLGPSDVSVYEMVGAYSTFPNHGFHTEPM
FITRIEDQNGNLVHQFTPKQKKVLSEETAFLMMHMLKGGMEEPGGTSQALWEYDLWKNGN
EIGGKTGTTSNHSDGWYMGVTKDLVTGVWVGGEDRSIHFRTSQLGEGSKTALPVYGLFME
RIYKDPALGYTMGRFPKPTVKITKEYNCTTVLPKQTLPDSAAVDSVLELLNIGNIL