Protein Info for CA264_20035 in Pontibacter actiniarum KMM 6156, DSM 19842

Annotation: QacE family quaternary ammonium compound efflux SMR transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 110 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details transmembrane" amino acids 31 to 49 (19 residues), see Phobius details amino acids 60 to 80 (21 residues), see Phobius details amino acids 86 to 105 (20 residues), see Phobius details PF00893: Multi_Drug_Res" amino acids 4 to 95 (92 residues), 104.3 bits, see alignment E=2.1e-34

Best Hits

Swiss-Prot: 59% identical to GDX_YERPE: Guanidinium exporter (gdx) from Yersinia pestis

KEGG orthology group: K11741, quaternary ammonium compound-resistance protein SugE (inferred from 60% identity to pph:Ppha_0763)

MetaCyc: 54% identical to guanidinium exporter (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-368; TRANS-RXN-369

Predicted SEED Role

"Quaternary ammonium compound-resistance protein SugE"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9YXH2 at UniProt or InterPro

Protein Sequence (110 amino acids)

>CA264_20035 QacE family quaternary ammonium compound efflux SMR transporter (Pontibacter actiniarum KMM 6156, DSM 19842)
MNAAWVYLVLAGICEIGWAFGLKYSEGFTKLGVSAVTVVVMILSFVLLSQAMKTLPLGTA
YAIWTGIGAAGTAILGIVFLNEPRDLIRIFCILLIVAGVVGLKVFSGSES