Protein Info for CA264_19730 in Pontibacter actiniarum KMM 6156, DSM 19842

Annotation: peptidylprolyl isomerase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 766 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details PF13616: Rotamase_3" amino acids 123 to 230 (108 residues), 85.2 bits, see alignment E=1e-27 amino acids 229 to 338 (110 residues), 98.1 bits, see alignment E=1e-31 PF00639: Rotamase" amino acids 133 to 228 (96 residues), 84 bits, see alignment E=2.4e-27 amino acids 240 to 335 (96 residues), 90.3 bits, see alignment E=2.7e-29 PF13145: Rotamase_2" amino acids 238 to 347 (110 residues), 36.2 bits, see alignment E=1.9e-12 PF00691: OmpA" amino acids 558 to 649 (92 residues), 59.7 bits, see alignment E=6.1e-20

Best Hits

Predicted SEED Role

"Survival protein SurA precursor (Peptidyl-prolyl cis-trans isomerase SurA) (EC 5.2.1.8)" in subsystem Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8)

Isozymes

Compare fitness of predicted isozymes for: 5.2.1.8

Use Curated BLAST to search for 5.2.1.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9YX37 at UniProt or InterPro

Protein Sequence (766 amino acids)

>CA264_19730 peptidylprolyl isomerase (Pontibacter actiniarum KMM 6156, DSM 19842)
MRSNQLLVAVAALAIAGCTATKKNDSKEPAIATLGSQPIPISEFRYVYEKNNSGNEDAYT
RQSLSDYLDLYTNFKLKVLEAEKRGLDTTTAFQRELEGYKEQLAQPYLTEKSVTDQLVKE
AYERMKQEVNASHILVSVASDATPEDTLAAYNRVMELRQRAQKGEDFGKLAQEHSQDPSA
ADNQGNLGYFTALQMVYPFEDAAYKTAVGQLSMPVRTRFGYHLIKVNDKRDARGEAKVAH
IMVRSKPDAPAADSLAAKQRVDAIYRRVQKGEDWGRLATEFSEDANSASNGGELPWFGTG
RMIPSFEEAAFGLQKPGEVSKPVYTPYGWHIVKLIEKRSLPPYEEMEQYLRNKIAKDSRS
ELNKTAFLKRIKQENNFTENTEAKAAALATATDELLQGKWSYSAEDKALKQTLFTIQGKP
YTVADFYTYVQEQQRPRSTGTATHAMGLLYDSFVDQMLFEYEKNNLANKYTDYRMLVQEY
HDGILLFQLMDEKVWSKAVEDSVGLRNFFNQNRDKYKWGERADAIVISAANKELLQQAQQ
QLEQRRYPVTFSKLTDMLFAQNKAELSAEGKAALREIAQMLQNNESLTLDVNGHTDARES
AKLADARAAAAVAYLQEQGVPAAQLSSNSYGKGRQAGPDNTETGRRRNRRVSFTLYTSEL
AALADNLNKKNPLAVQITEKKFQRGENKALDAVDWKAGSYTMQQNGREYLIIVKDVLEPG
YKELDEVRGLAISDYQNYLEEQWVQELRTKYPVEIRESEVEKLVQK