Protein Info for CA264_18675 in Pontibacter actiniarum KMM 6156, DSM 19842

Annotation: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 165 TIGR01670: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family" amino acids 14 to 162 (149 residues), 147 bits, see alignment E=4.2e-47 PF08282: Hydrolase_3" amino acids 86 to 149 (64 residues), 27.1 bits, see alignment E=5.3e-10

Best Hits

Swiss-Prot: 40% identical to KDSC_SALTI: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC (kdsC) from Salmonella typhi

KEGG orthology group: None (inferred from 51% identity to lan:Lacal_2180)

MetaCyc: 41% identical to 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase monomer (Escherichia coli BL21(DE3))
3-deoxy-manno-octulosonate-8-phosphatase. [EC: 3.1.3.45]

Predicted SEED Role

"3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (EC 3.1.3.45)" in subsystem KDO2-Lipid A biosynthesis (EC 3.1.3.45)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.3.45

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9YWT2 at UniProt or InterPro

Protein Sequence (165 amino acids)

>CA264_18675 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (Pontibacter actiniarum KMM 6156, DSM 19842)
MSITQTDLTRINTFVFDVDGVLTDGLLYCFADGEQVRAFNIKDGFAIKHAISQGYRVAII
SGKNEPGVRKRLSQLGIEDIFLGIEDKVDALEDYIYTQGIHPATVAYMGDDMPDFEVMQR
CGLRACPADAADDIRAIATFVSTKNGGRGAVRELVEQVMKAQDTW