Protein Info for CA264_18415 in Pontibacter actiniarum KMM 6156, DSM 19842

Annotation: alanine dehydrogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF05222: AlaDh_PNT_N
  • amino acids 7 to 138 (132 residues), 69.1 bits, E=2.3e-23

Best Hits

KEGG orthology group: None (inferred from 55% identity to mtt:Ftrac_2781)

Predicted SEED Role

"Lysine ketoglutarate reductase (EC 1.5.1.8) (LKR) / Saccharopine dehydrogenase (EC 1.5.1.9)" in subsystem Lysine degradation (EC 1.5.1.8, EC 1.5.1.9)

MetaCyc Pathways

• L-lysine degradation XI (2/5 steps found)
• superpathway of L-lysine degradation (6/43 steps found)

KEGG Metabolic Maps

• Lysine biosynthesis
• Lysine degradation

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.5.1.8 or 1.5.1.9

Sequence Analysis Tools

See A0A1X9YWN8 at UniProt or InterPro

Protein Sequence (414 amino acids)

>CA264_18415 alanine dehydrogenase (Pontibacter actiniarum KMM 6156, DSM 19842)
MRKLKIGIIKEGKVPVDKRVPLTPKKCQEALQEFPEMEIAVQPSDIRCFTDEEYCELQIP
LQEDLRDCDVLMGVKEVPTEQLIPDKTYLFFSHTIKEQPQNAKLLRAVLDKNITLIDYEL
LKTTDGQRVVAFGRYAGIVGAYNGILTYGKKHELFNLKPAYLCHEMEDMQEEYFKVKLPP
IKIAVTGGGRVAGGAMEVLDKMEIRKVSVFDFLYKQFTEPVYAQLHSGDYNARPDVEVWD
SPDFYANPHLYKSTFRKFTRVTDLLMACAYWDPRAPKLFTEEDARQPDFKIDTIADITCD
VNGSIPATKRSTTITSPAYDYNPTTGELEEAYARPDNITIMAVDNLPCELPRNASRDFGR
HLIDNVFPHFFNGDEEGILKRATIAKGGKLTERYSYLQGYADSAATNKEKQAAV