Protein Info for CA264_17795 in Pontibacter actiniarum KMM 6156, DSM 19842

Annotation: dephospho-CoA kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 198 PF01121: CoaE" amino acids 4 to 178 (175 residues), 156.5 bits, see alignment E=3.1e-50 TIGR00152: dephospho-CoA kinase" amino acids 4 to 178 (175 residues), 133.2 bits, see alignment E=5e-43

Best Hits

Swiss-Prot: 41% identical to COAE_BACTN: Dephospho-CoA kinase (coaE) from Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482)

KEGG orthology group: K00859, dephospho-CoA kinase [EC: 2.7.1.24] (inferred from 50% identity to chu:CHU_2441)

Predicted SEED Role

"Dephospho-CoA kinase (EC 2.7.1.24)" in subsystem Coenzyme A Biosynthesis (EC 2.7.1.24)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.1.24

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9YW34 at UniProt or InterPro

Protein Sequence (198 amino acids)

>CA264_17795 dephospho-CoA kinase (Pontibacter actiniarum KMM 6156, DSM 19842)
MLKIGITGGMGVGKTIVTHMFAVLGVPVYDADSRAKWVMHHHEALRQELLHAFGPETFSE
QGELNRTYLAGVVFNNPQRLAQLNSLVHPHVRDDFEVWVASHADKPYVLKEAALMYESEA
WKQMDEVIAVYAPMEVRLKRLAHRDAHRTEAEIKAIIAKQLSEEEKMRRAQHVLCNDDRQ
LVIPQVLALHKSFSSRGA