Protein Info for CA264_17605 in Pontibacter actiniarum KMM 6156, DSM 19842

Annotation: glutamine--fructose-6-phosphate aminotransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR01135: glutamine-fructose-6-phosphate transaminase (isomerizing)
  • amino acids 2 to 611 (610 residues), 835.4 bits, E=1.4e-255
• PF13522: GATase_6
  • amino acids 63 to 193 (131 residues), 74.6 bits, E=1.6e-24
• PF13537: GATase_7
  • amino acids 80 to 196 (117 residues), 49.8 bits, E=6.4e-17
• PF01380: SIS
  • amino acids 292 to 419 (128 residues), 119.9 bits, E=1.3e-38
  • amino acids 466 to 593 (128 residues), 101.7 bits, E=5.6e-33

Best Hits

Swiss-Prot: 64% identical to GLMS_BACTN: Glutamine--fructose-6-phosphate aminotransferase [isomerizing] (glmS) from Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482)

KEGG orthology group: K00820, glucosamine--fructose-6-phosphate aminotransferase (isomerizing) [EC: 2.6.1.16] (inferred from 76% identity to chu:CHU_3838)

Predicted SEED Role

"Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] (EC 2.6.1.16)" in subsystem Sialic Acid Metabolism or UDP-N-acetylmuramate from Fructose-6-phosphate Biosynthesis (EC 2.6.1.16)

MetaCyc Pathways

• O-antigen building blocks biosynthesis (E. coli) (8/11 steps found)
• UDP-N-acetyl-D-glucosamine biosynthesis I (3/5 steps found)
• UDP-N-acetyl-D-glucosamine biosynthesis II (3/6 steps found)
• chitin biosynthesis (5/9 steps found)
• UDP-N-acetyl-D-galactosamine biosynthesis III (2/6 steps found)
• CMP-legionaminate biosynthesis I (3/10 steps found)
• superpathway of UDP-N-acetylglucosamine-derived O-antigen building blocks biosynthesis (6/24 steps found)
• superpathway of mycolyl-arabinogalactan-peptidoglycan complex biosynthesis (10/33 steps found)

KEGG Metabolic Maps

• Aminosugars metabolism
• Glutamate metabolism
• Nucleotide sugars metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.6.1.16

Sequence Analysis Tools

See A0A1X9YW92 at UniProt or InterPro

Protein Sequence (611 amino acids)

>CA264_17605 glutamine--fructose-6-phosphate aminotransferase (Pontibacter actiniarum KMM 6156, DSM 19842)
MCGIVAYVGHREASPIIIKGLKRLEYRGYDSAGIALMNGKLNIYKKKGKVAELEAFIATQ
DTHSSIGMGHTRWATHGEPNDENAHPHYSTSGNIAIIHNGIIENYASLKKLLMEKGHTFK
SETDSEVFINLIEDIRTNNNCTLPEAVRLAMHEVVGAYAIVVLSQDSPNQLIAARKGSPL
VVGIGEGEYFLASDATPIIEYTNEVVYLNDFELAIINNGQLDIRTKEDVQQTPYVQKLEM
ELESIEKGGYEHFMLKEIFEQPRSILDSMRGRMIAESDHLMMAGIREFENKFVNANRIII
VACGTSWHAGLVAEYLIEDLARIPVEVEYASEFRYRNPILNERDIVIAISQSGETADTLA
ALELAKSKGATIFGICNVVGSSIARATDAGAYTHAGPEIGVASTKAFTAQVTVLTLIAMI
IGSKRGTLETTKLRELMVELETIPSKVEEALQLNEQIVQISEQYKDATNFLYLGRGYNFP
VALEGALKLKEISYIHAEGYPAAEMKHGPIALIDEQMPVVVIATKDSSYEKIVSNVQEVK
ARKGKVIAVVTEGDTTIPAMADHVIEIPETSEHLMPLLSVIPLQLLSYHIAVMRGCNVDQ
PRNLAKSVTVE