Protein Info for CA264_17545 in Pontibacter actiniarum KMM 6156, DSM 19842

Annotation: single-stranded-DNA-specific exonuclease RecJ

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 568 TIGR00644: single-stranded-DNA-specific exonuclease RecJ" amino acids 26 to 565 (540 residues), 531.8 bits, see alignment E=8.1e-164 PF01368: DHH" amino acids 80 to 229 (150 residues), 92.3 bits, see alignment E=4.4e-30 PF02272: DHHA1" amino acids 322 to 442 (121 residues), 66.6 bits, see alignment E=5.1e-22 PF17768: RecJ_OB" amino acids 458 to 564 (107 residues), 100.9 bits, see alignment E=6.1e-33

Best Hits

KEGG orthology group: K07462, single-stranded-DNA-specific exonuclease [EC: 3.1.-.-] (inferred from 59% identity to dfe:Dfer_4050)

Predicted SEED Role

"Single-stranded-DNA-specific exonuclease RecJ (EC 3.1.-.-)" in subsystem DNA-replication or DNA Repair Base Excision or DNA repair, bacterial RecFOR pathway (EC 3.1.-.-)

Isozymes

Compare fitness of predicted isozymes for: 3.1.-.-

Use Curated BLAST to search for 3.1.-.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9YWB5 at UniProt or InterPro

Protein Sequence (568 amino acids)

>CA264_17545 single-stranded-DNA-specific exonuclease RecJ (Pontibacter actiniarum KMM 6156, DSM 19842)
MEKRWVISQEAPVEVVQQLAEQLKISSTLASILCQRGICTFDEAKHFFRPSLQDLHDPFL
MKDMDQAVNRLNNALHSNEKILVYGDYDVDGTTSVALMYGFLRNYTSNIDFYIPDRYKEG
YGVSSQGIDWAAENGFTLIISLDCGIKSADKVAYASEKGIDFIICDHHLPDEDIPQAVAV
LDPKRVDCPYPYKELSGCGVGFKLLQAFCIQNNIEQEEAYKLLDLLVVSIAADIVPITGE
NRILAYFGLQHLNGPQPMRPGLDALKELADIRSEMDITSIVFGFAPRINAAGRMGDAKNS
VRMLLAQTKEEAFKMADIINESNKERRSKDTNITKEALQMIEQDEFLRTANSTVLFKETW
HKGVIGIVASRCIEHYYRPTIILTQSNGKASGSARSVHGFNVHSAIESCSDLLEQFGGHM
YAAGLTLPVENVPAFIERFERVVTDTITEEQKIPQIEIDAPINLKQITRNFYNIIRQMEP
FGPGNMRPVFVSECVYDTGSVRVVGDSHLKLRLTQDGFTSIDAIGFGLGDYYKAISKGIP
FDVCYTVEENIYRGVITLQLRIKDIRIK