Protein Info for CA264_17325 in Pontibacter actiniarum KMM 6156, DSM 19842

Annotation: isoleucine--tRNA ligase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1117 TIGR00392: isoleucine--tRNA ligase" amino acids 7 to 905 (899 residues), 995 bits, see alignment E=1.6e-303 PF00133: tRNA-synt_1" amino acids 19 to 697 (679 residues), 403.6 bits, see alignment E=1.9e-124 PF09334: tRNA-synt_1g" amino acids 51 to 195 (145 residues), 30.2 bits, see alignment E=4.2e-11 amino acids 631 to 706 (76 residues), 27.7 bits, see alignment 2.5e-10 PF08264: Anticodon_1" amino acids 746 to 898 (153 residues), 113.2 bits, see alignment E=2.1e-36 PF19302: DUF5915" amino acids 917 to 1111 (195 residues), 183.4 bits, see alignment E=7.2e-58

Best Hits

KEGG orthology group: K01870, isoleucyl-tRNA synthetase [EC: 6.1.1.5] (inferred from 63% identity to aas:Aasi_0436)

Predicted SEED Role

"Isoleucyl-tRNA synthetase (EC 6.1.1.5)" (EC 6.1.1.5)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 6.1.1.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9YVZ4 at UniProt or InterPro

Protein Sequence (1117 amino acids)

>CA264_17325 isoleucine--tRNA ligase (Pontibacter actiniarum KMM 6156, DSM 19842)
MVKYNEYKNLNYAKVGEDVLEFWKKNNIFEKSVATREGNAPFVFYEGPPSANGKPGIHHV
MARAVKDIFCRYKTLKGFQVNRKGGWDTHGLPIELQVEKELGITKEDIGKTISVEEYNQR
CRETVMRFKNQWDTLTEQMGYWVDLNNPYITFENEYIESCWALLRRLYDKGYLYKGYTIQ
PFSPAAGTGLSSHELNQPGCYKMVKDTTIVAQFEVKKITRNMFLFENEDEKVYFLAWTTT
PWTLPANTGLAVGKGIKYVKVKSFNPYTYEPISVVLGKDLVGRYFNPKAADLALEDFKPG
DKLIPFKVVEEFTGADLNGVEYHQLLPYVQPEKPAFRVVIGDFVTTEDGTGIVHISPTFG
ADDARVAAQNDIPSLLVLDENGKLGPIVDRQGRFVKEITDFAGMYVKNYNGEDENGVDYK
PTDVKIAIKLKEEGKAFKVEKYEHTYPHCWRTDKPVLYYPLDSWFIKTTAVKDRLIELNK
TINWKPESTGTGRFGNWLENLVDWNLSRSRYWGTPLPIWRTEDGEEEICIGSIAELNEEI
AKAVQAGVMDANVEVKDLHRPYVDNIILLSKSGKAMYREPDLIDVWFDSGAMPYAQWHYP
IENKEIFEKNFPADFIAEGVDQTRGWFFTLHALAVMLEDSVAYKNVIANGLVLDKNGNKM
SKRLGNAIDPFEMIGQYGPDAVRWYMIANAPPWDNLKFNPDGVVETQRRFFGTLQNTYSF
FALYANLDNFTYAEADVPLAQRTESDRWIISKLNTLVQDVDSYYADYDPTRAARAIQDFV
VDDLSNWYVRLNRKRFWKGEYNTDKMAAYQTLYTCLETVAKLASPVAPFYAEQLFLDLNS
VSGRNEVESVHLALYPEVAEGAIDMDLEERMQLAQTVSSLVHSLRKKEMIKVRQPLQRIL
IPVLNNRMRAQIDAVADLILSEVNVKTIEFIDDTSGVLVKKIKPNFKKLGQVFGPKMKLV
AAAVQRMDQNDIATLEREGGFEVMLNDEETAVLTPDDVEISSEDIPGWLVASEGKLTVAL
DITLTEELKQEGIARDLVNRIQNLRKDTNLEVQDKIHILLQRSMPEVTAAIENYSDYICA
ETQALSLDTVENLESATLLDIDEYKVYIQIQTEKASV