Protein Info for CA264_17265 in Pontibacter actiniarum KMM 6156, DSM 19842

Annotation: exodeoxyribonuclease III

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 253 TIGR00195: exodeoxyribonuclease III" amino acids 1 to 252 (252 residues), 294.4 bits, see alignment E=7.9e-92 TIGR00633: exodeoxyribonuclease III (xth)" amino acids 1 to 252 (252 residues), 305 bits, see alignment E=4.4e-95 PF03372: Exo_endo_phos" amino acids 4 to 225 (222 residues), 91.7 bits, see alignment E=2.8e-30

Best Hits

Swiss-Prot: 43% identical to EXOA_BACSU: Exodeoxyribonuclease (exoA) from Bacillus subtilis (strain 168)

KEGG orthology group: K01142, exodeoxyribonuclease III [EC: 3.1.11.2] (inferred from 68% identity to chu:CHU_3497)

Predicted SEED Role

"Exodeoxyribonuclease III (EC 3.1.11.2)" in subsystem DNA repair, bacterial (EC 3.1.11.2)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.11.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9YVU2 at UniProt or InterPro

Protein Sequence (253 amino acids)

>CA264_17265 exodeoxyribonuclease III (Pontibacter actiniarum KMM 6156, DSM 19842)
MKIITYNVNGIRAALTKGFGDWLKAANPDVLCLQEIKADESKFDKALFEDMGYHVYLHPA
VKKGYSGVAILSKDKPQHVEIGCGMDCYDVEGRVIRADYGDVSVMSVYMPSGSSGEERQG
FKFQWMDDFHGYVGDLKQTLPGLVVSGDYNICHKPIDIHNPKSNAKSSGFLPEEREWMGK
LVDTGFIDTFRHFNQEPHNYTWWSYRAGARNKNLGWRIDYNMATDNLRDRLKRAAILTEA
KHSDHCPVLLELE