Protein Info for CA264_17130 in Pontibacter actiniarum KMM 6156, DSM 19842

Annotation: histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 973 transmembrane" amino acids 12 to 32 (21 residues), see Phobius details amino acids 315 to 336 (22 residues), see Phobius details PF03924: CHASE" amino acids 80 to 267 (188 residues), 209.3 bits, see alignment E=2.1e-65 TIGR00229: PAS domain S-box protein" amino acids 347 to 469 (123 residues), 63.1 bits, see alignment E=1.4e-21 amino acids 472 to 595 (124 residues), 91.9 bits, see alignment E=1.7e-30 PF00989: PAS" amino acids 347 to 460 (114 residues), 37.5 bits, see alignment E=9.4e-13 amino acids 476 to 586 (111 residues), 50.6 bits, see alignment E=8.2e-17 PF13426: PAS_9" amino acids 356 to 462 (107 residues), 44.2 bits, see alignment E=9.2e-15 amino acids 487 to 588 (102 residues), 46 bits, see alignment E=2.4e-15 PF08448: PAS_4" amino acids 482 to 588 (107 residues), 48.8 bits, see alignment E=3.4e-16 amino acids 610 to 721 (112 residues), 39.4 bits, see alignment E=2.9e-13 PF08447: PAS_3" amino acids 498 to 582 (85 residues), 59.2 bits, see alignment E=1.8e-19 PF00512: HisKA" amino acids 749 to 813 (65 residues), 30.5 bits, see alignment 1.3e-10 PF02518: HATPase_c" amino acids 861 to 966 (106 residues), 89.1 bits, see alignment E=1.2e-28 PF14501: HATPase_c_5" amino acids 862 to 953 (92 residues), 23.8 bits, see alignment E=1.6e-08

Best Hits

Predicted SEED Role

"diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s)" in subsystem Bacterial hemoglobins

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9YVQ5 at UniProt or InterPro

Protein Sequence (973 amino acids)

>CA264_17130 histidine kinase (Pontibacter actiniarum KMM 6156, DSM 19842)
MKFARLASFIRDYFIAVFSFLLIFLLTFFIYSETKKKAEERSAKMFSLRAEQVTESINKR
MRDYIQILIGGKALFISADTVTRKDWHTYYKTLNLEENYPGMQGFGYAVVLNADNVPAHV
KMIRKEGFKNYGIYPEGKRDVYTSIVYLEPFSDRNLRAFGYDMFSEPVRQSAMRIARDTR
QPAMSGKVRLMQETGKDEQAGFLIYLPVYENNAEPESIQERQRLIKGYVYSPFRAKDLMM
AVLTDDFQDLDVEVYDGSKLAKEDLLFSTDSTLYYHTDHDREYSELNTITIGNHTWRLYI
SAKAGFSRSADSELPYFILLGGSIISFLMFFIIWSLSNTRRSNRLKQTITDNATAALFII
DEKGYCTFMNPAAEEMTGFTFEEMQEKTLHDMVHYKYADGSPYPVSMCPIRSALTINKPM
RAYEDMFVRKDGTMFNVMCAVQPIVESGSESYAIIEVRDITDEKQAQQAIIESEARFRNM
ADSAPVMIKVMDDASNFLYVNKQWLDFTGISFEDTINMSWKEVVHPDDIEEKERLTNEAI
KEQVVFRVEYRMRRFDGEYRWVVGTNTPRFGANGDFLGYIGSVIDITEIKEAERKVKQNA
ELLQKLFLEVPAVVGLVRHPDFQYVLANPQYRKLYGNRPLVGKTIYEAHSEQEGRGFFGR
LEEVFRTGQPFIGNEVSTAIDRNNSGEVVYGYFNLVYQPLIDPDGKVEAVLVFAVEVTEL
VNARKELLLTNDELSGKNDELLRINNDLDNFVYTASHDLKSPIANMEGLATLLRDILQGK
LEAEDMQVLDMVQNAINKLKGTIADLAEITKVQKELHSSVEPLSFEHMLQDITADISGMV
QEAGAVFKTDLQVENILYARKNLRSIIYNLVSNAIKYKAPQRKPEVCISTYLQEGYVVLE
VKDNGLGIKKEQQHKLFSMFKRLHSHVEGTGIGLYIVKRIIENNGGKIEVESELGKGTTF
RVYFKEAAVVQEV