Protein Info for CA264_17000 in Pontibacter actiniarum KMM 6156, DSM 19842

Annotation: phytoene dehydrogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details PF00890: FAD_binding_2" amino acids 4 to 39 (36 residues), 21.1 bits, see alignment 4.8e-08 TIGR02734: phytoene desaturase" amino acids 4 to 484 (481 residues), 362.3 bits, see alignment E=2.1e-112 PF01266: DAO" amino acids 4 to 405 (402 residues), 54.9 bits, see alignment E=3.3e-18 PF13450: NAD_binding_8" amino acids 6 to 60 (55 residues), 49.3 bits, see alignment 1.4e-16 PF01593: Amino_oxidase" amino acids 11 to 479 (469 residues), 98.1 bits, see alignment E=2.2e-31

Best Hits

Swiss-Prot: 53% identical to CRTDH_FLAS9: 1-hydroxycarotenoid 3,4-desaturase (crtD) from Flavobacterium sp. (strain P99-3)

KEGG orthology group: None (inferred from 58% identity to fte:Fluta_0097)

Predicted SEED Role

"Phytoene desaturase, neurosporene or lycopene producing (EC 1.3.-.-) / 4,4'-diapolycopene oxidase" in subsystem Carotenoids (EC 1.3.-.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.3.-.-

Use Curated BLAST to search for 1.3.-.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9YVP1 at UniProt or InterPro

Protein Sequence (500 amino acids)

>CA264_17000 phytoene dehydrogenase (Pontibacter actiniarum KMM 6156, DSM 19842)
MAKAVIIGAGIGGIATAVRLAVKGYSVTVLEANDTFGGKMQEFWLGGYRFDAGPSLFTLP
HLVDELFTLAGRNPKEYFTYTRLDPITHYFWPDGSRVKAYADAAQFATEAAQQLGVPRKA
VQEALEKSSRLYKGTADTFLHKSLHRLQTYLSPDVLKAMGCLTDLGLTTTMHEANAKQFS
DPRFVQLLDRFATYNGSDPYQAPGTLNIIPHLEHNLGAFYPKGGIYAIAASLVRLAEELG
VVFRYQEPVLRITTENGKATGVETNSGSYQADVVVSNMDVVPTYRKLLPNQPAPEKTLQQ
PRSSSALIFYWGIKRDFPQLHVHNIFFSQDYKAEFEHIFKYKTVSQDPTVYVNITSKAAP
GDAPAGSENWFVMVNVPHNQGQDWEELTAKTRQAVLQKLSRMLQTDIKELIEEEQVLDPL
LIEGRTSSFGGALYGSSSNNRMAAFLRHPNFSARLKGLYFCGGSVHPGGGIPLCLLSAKI
VGELTPAVVPSPAKPPKSHA