Protein Info for CA264_15870 in Pontibacter actiniarum KMM 6156, DSM 19842

Annotation: long-chain fatty acid--CoA ligase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 PF00501: AMP-binding" amino acids 26 to 408 (383 residues), 252.1 bits, see alignment E=8.2e-79 PF13193: AMP-binding_C" amino acids 459 to 538 (80 residues), 68.7 bits, see alignment E=6.9e-23

Best Hits

KEGG orthology group: K00666, fatty-acyl-CoA synthase [EC: 6.2.1.-] (inferred from 58% identity to sdl:Sdel_0570)

Predicted SEED Role

"Medium-chain-fatty-acid--CoA ligase (EC 6.2.1.-)" (EC 6.2.1.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 6.2.1.-

Use Curated BLAST to search for 6.2.1.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9YV88 at UniProt or InterPro

Protein Sequence (550 amino acids)

>CA264_15870 long-chain fatty acid--CoA ligase (Pontibacter actiniarum KMM 6156, DSM 19842)
MANTRILPPTPRAYQSKLLIKEIFNQSLKYEPDREIVYRDLLRLSYKEMNKRVPRLAHLL
TTHLQIEQGQTVAFLDYDSHRYLEAYFAVPMVGAVLHMINFRLSPEEILYTINHAEDTVI
FCHEDFLPILESLQGRMETVQRVVLLSDSGATPDTPLELSGEYEELLLQQPDTYNFPDFS
EDTVATTFYTTGTTGLPKGVYFSHRQLVLHTFGLATSLGAMDNALKIGSNDVYMPITPMF
HVHAWGFPYLATFLGMQQVYPGRYEPAMLLKLVLQEKVTVSHCVPTILQMLVNHPQVKTF
DLTNWKVVIGGSALPRGLAMAAMDLGIEVITGYGMSETCPVLSLTYLNRKTMRHLTEEEE
ADLRVKTGRPIQMVDIRLMNEEGQFLPNDGKSTGEIVVRAPWLTQGYYKDEERSLELWKH
GYLHTGDIATIAPDGVITITDRKKDVIKSGGEWISSLLLESLISQHPDVQETAVVAVPDQ
RWQERPLALVVARPGANLTDEELIRHMEQFSDSGRISHYAVPKQFKFVSEIPKTSVGKID
KKRIKKELEV