Protein Info for CA264_15820 in Pontibacter actiniarum KMM 6156, DSM 19842

Annotation: transcription-repair coupling factor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1123 PF17757: UvrB_inter" amino acids 149 to 232 (84 residues), 79.1 bits, see alignment 6.6e-26 TIGR00580: transcription-repair coupling factor" amino acids 242 to 1047 (806 residues), 935.5 bits, see alignment E=2.2e-285 PF02559: CarD_TRCF_RID" amino acids 438 to 494 (57 residues), 60.6 bits, see alignment 3.9e-20 PF04851: ResIII" amino acids 563 to 719 (157 residues), 32.1 bits, see alignment E=3.2e-11 PF00270: DEAD" amino acids 564 to 723 (160 residues), 81.7 bits, see alignment E=1.6e-26 PF00271: Helicase_C" amino acids 762 to 867 (106 residues), 75.6 bits, see alignment E=1.1e-24 PF03461: TRCF" amino acids 976 to 1066 (91 residues), 85.8 bits, see alignment E=6.3e-28

Best Hits

KEGG orthology group: K03723, transcription-repair coupling factor (superfamily II helicase) [EC: 3.6.4.-] (inferred from 65% identity to dfe:Dfer_3695)

Predicted SEED Role

"Transcription-repair coupling factor" in subsystem DNA-replication or Transcription factors bacterial

Isozymes

Compare fitness of predicted isozymes for: 3.6.4.-

Use Curated BLAST to search for 3.6.4.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9YV79 at UniProt or InterPro

Protein Sequence (1123 amino acids)

>CA264_15820 transcription-repair coupling factor (Pontibacter actiniarum KMM 6156, DSM 19842)
MKVKDFLELYRLDSVVQTLAQRLKATEPYRLQIKGLAGSQDAVLASAVYTLNYGHQLFVM
HDKEEAAYFYTDLKNLLGEEKEILLFPTSYKRPYSFDDTENANILMRAEVLNRLNQKTGK
GELIVTYPEALTEKVINKKSLVENTLGAKIGEKLDTTFLSEMLAEYGFERTEFVYEAGQY
AVRGGIVDVYSYANDLPYRIELFGDEIESIRTFDPDTQLSVETKKAISIIPNVQTKLLQE
TREAFLDFLPNNTTLWFKDVRLTLDVIDEYFDKASHNFEKMMATSGGTQIVSDPEQLFQT
QKQFKKLLEKYTVVEIGKRFHFKNTEVMQLQAKPQPSFNKDFKRLVKDLHEQQGAGFVNV
IATDSPRQINRLTMIFDELDHDVRFQHLPVSLREGFIDQTLKITCYTDHQLFDRFYQHKA
KTGHSKSKAMTLKELRSLQPGDYVTHTDYGIGRFAGLEKVEVGGRLQEAIRLVYRDDDLL
YVSIHALHKISKYSGKEGGPPSMSKLGSPEWENKKKKVKSKVKDIAHELISLYAKRKAAP
GYAYTRDGFLQAELESSFIYEDTPDQGKATEDVKADMEQPHPMDRLVCGDVGFGKTEIAI
RAAFKAACDGKQVAILVPTTILAMQHYRTFRDRLEQFPVTVDYVNRFKTAKDTKDTLKRV
AEGKVDILIGTHRIVSKDVKFKDLGLMIIDEEQKFGVKTKEKLKEMKINVDTLTLTATPI
PRTLHFSLMGARDLSVIATPPPNRQPVKTELHVFDEALIRDAIVYEMKRGGQVFFVHNRI
KDIEEIAAMILRHVPDCKVTYAHGQMEPEKLEKRMMKFVNGEYDVLVSTNIIESGLDIEN
ANTIIINRAHMFGLSDLHQMRGRVGRSNKKAYCYLLTPPVAGLPSDARKRLSTLEEFSDL
GEGFKIAMRDLDIRGAGNLLGGEQSGFITDLGFEMYHQVLDDAIKELKETEFRDLFLNDN
LAEFIEPVRECNIETDMEVLIPDWYVSNISERLNLYSKLDSTKDLQELEKLRESIVDRFG
PLPEAVQQLVEIVKLRWQAQQLGFEKLTIKKEVMKGYLPSENNDKYFQSDVFGNILKYVQ
QHPRKSRLKEAKHKLIVIVEDIQSIADAKEVFEGLGIKEAVSA