Protein Info for CA264_15725 in Pontibacter actiniarum KMM 6156, DSM 19842

Annotation: polyphosphate kinase 1

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 704 TIGR03705: polyphosphate kinase 1" amino acids 15 to 682 (668 residues), 786.9 bits, see alignment E=8.7e-241 PF13089: PP_kinase_N" amino acids 15 to 120 (106 residues), 128.5 bits, see alignment E=3.2e-41 PF02503: PP_kinase" amino acids 130 to 313 (184 residues), 158.1 bits, see alignment E=5.1e-50 PF17941: PP_kinase_C_1" amino acids 340 to 502 (163 residues), 228.8 bits, see alignment E=7.3e-72 PF13091: PLDc_2" amino acids 382 to 497 (116 residues), 27 bits, see alignment E=8.4e-10 amino acids 527 to 649 (123 residues), 35.2 bits, see alignment E=2.5e-12 PF13090: PP_kinase_C" amino acids 511 to 665 (155 residues), 239 bits, see alignment E=5.2e-75

Best Hits

KEGG orthology group: K00937, polyphosphate kinase [EC: 2.7.4.1] (inferred from 46% identity to hhy:Halhy_5961)

Predicted SEED Role

"Polyphosphate kinase (EC 2.7.4.1)" in subsystem High affinity phosphate transporter and control of PHO regulon or Phosphate metabolism or Purine conversions (EC 2.7.4.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.4.1

Use Curated BLAST to search for 2.7.4.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9YV76 at UniProt or InterPro

Protein Sequence (704 amino acids)

>CA264_15725 polyphosphate kinase 1 (Pontibacter actiniarum KMM 6156, DSM 19842)
MDKEKEKEAKTAYPFINRELSWLAFNYRVLQEAKDKSVPLLERVKFMAIFSSNLDEYFKV
RVATLKRLIKLKKKTRKKLEEDPTETLDQIMAEVHRQQQELGEVFRDGILADLREHDIHL
LTEHDLNPGQEAWVQEYFDKTLEPLLLPIILDETETHLFLKDQTVYLGVKMWEPTAADCM
PERFAMLEIPTKKHGTRFVKLPTVGDQRYVMFMDDVIRFCLPRLFPNYSTFDAHAVKVSR
DAELDIEEEVSGNLMAKIRNSLKKRETGYPARLLYDPETPQDLLDRMMAHTGITEEALVE
GSKYHNFRDFFQFPDFNLPDLKYKPQPTLVHPQLEQEPKMLAAMKERDYMVHYPYQSFDY
VLRLFEEAAVDPKVTAVSATLYRVANKSKVAKALAKAAKNGKLVTVVVELKARFDEESNI
YWAGKLQKAGANVIFGIQDLKVHSKLGLITRNERGKLVNYAYLSTGNYNEETSKVYADHA
LFTSDKRLTKDVEQVFNFFIDKQTDKEFEHLLMAPLNMRQGFAKLVDQEIKNAKKGLPAR
VTLKMNALQDERMIKKLYAASQAGVKVQLLVRGICCLVPGVEGLSENIQVRSIVDRYLEH
ARVYIFHNNGEEKLYIASADWMTRNLNRRVEVAFPIYQEDLAQQIRTIIDLQLADDTKTR
SVDNSYIKPHAPTHVRAQYAIYNYLRELVPPTPETACERSEEEQ