Protein Info for CA264_15645 in Pontibacter actiniarum KMM 6156, DSM 19842
Annotation: ornithine--oxo-acid transaminase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 62% identical to OAT_HUMAN: Ornithine aminotransferase, mitochondrial (OAT) from Homo sapiens
KEGG orthology group: K00819, ornithine--oxo-acid transaminase [EC: 2.6.1.13] (inferred from 72% identity to chu:CHU_0647)MetaCyc: 62% identical to Ornithine aminotransferase (Homo sapiens)
Ornithine aminotransferase. [EC: 2.6.1.13]
Predicted SEED Role
"Ornithine aminotransferase (EC 2.6.1.13)" in subsystem Arginine and Ornithine Degradation or Dimethylarginine metabolism (EC 2.6.1.13)
MetaCyc Pathways
- L-citrulline biosynthesis (7/8 steps found)
- L-arginine degradation VI (arginase 2 pathway) (4/4 steps found)
- L-arginine degradation I (arginase pathway) (3/3 steps found)
- L-ornithine biosynthesis II (3/3 steps found)
- L-proline biosynthesis III (from L-ornithine) (3/3 steps found)
- L-arginine degradation XIII (reductive Stickland reaction) (4/5 steps found)
- superpathway of L-citrulline metabolism (9/12 steps found)
- L-Nδ-acetylornithine biosynthesis (5/7 steps found)
KEGG Metabolic Maps
Isozymes
No predicted isozymesUse Curated BLAST to search for 2.6.1.13
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A1X9YUZ9 at UniProt or InterPro
Protein Sequence (413 amino acids)
>CA264_15645 ornithine--oxo-acid transaminase (Pontibacter actiniarum KMM 6156, DSM 19842) MSTQTINSSQEAIDIEHQYGAHNYHPLPVVLSRGEGVHLWDVEGKHYYDFLSAYSAVNQG HCHPKIVGALVEQAQQLTLTSRAFYNDKLGPAEKYICEYFNYDKALFMNSGAEAVETAIK LARKWGYMKKGIAPHNAEIIVVEHNFHGRTTGIISFSTDPDSTKGFGPYMPGYKVIPYND ADALEQALKENPNVCGFLVEPIQGEAGVMVPDEGYLAKAHALCKEYDVLLMADEIQTGIG RTGKLLASYYDDVKADILILGKALSGGVLPVSCVLANDDIMLCIQPGEHGSTFGGNPLAA VVAIAALEVIKEESLTENANRLGELFRERMRRLMDKRPELVTLVRGRGLLNAIVVQPTAD GRTAWDVCVELKNHGLLAKPTHGDIIRFAPPLVMTEEQLNECCDIIENVILSF