Protein Info for CA264_15255 in Pontibacter actiniarum KMM 6156, DSM 19842

Annotation: alpha/beta hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00561: Abhydrolase_1
  • amino acids 21 to 130 (110 residues), 43.3 bits, E=5.4e-15
  • amino acids 181 to 237 (57 residues), 30.2 bits, E=5.4e-11
• PF12697: Abhydrolase_6
  • amino acids 22 to 241 (220 residues), 40.8 bits, E=6.4e-14

Best Hits

KEGG orthology group: None (inferred from 68% identity to sli:Slin_0656)

Predicted SEED Role

"2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase (EC 3.7.1.-)" in subsystem Biphenyl Degradation or Central meta-cleavage pathway of aromatic compound degradation or carbazol degradation cluster (EC 3.7.1.-)

KEGG Metabolic Maps

• 1,1,1-Trichloro-2,2-bis(4-chlorophenyl)ethane (DDT) degradation
• Ascorbate and aldarate metabolism
• Benzoate degradation via CoA ligation
• Benzoate degradation via hydroxylation
• Biphenyl degradation
• Caprolactam degradation
• Ethylbenzene degradation
• Inositol phosphate metabolism
• Limonene and pinene degradation
• Nicotinate and nicotinamide metabolism
• Phenylalanine metabolism

Isozymes

Compare fitness of predicted isozymes for: 3.7.1.-

Use Curated BLAST to search for 3.7.1.-

Sequence Analysis Tools

See A0A1X9YUU8 at UniProt or InterPro

Protein Sequence (257 amino acids)

>CA264_15255 alpha/beta hydrolase (Pontibacter actiniarum KMM 6156, DSM 19842)
MDLQVRQEGEYQYIDEGEGEVLLLLHGLFGALSNWNGVVEHFSKNYRVVIPLMPIYEMPL
HKAGVPGLVKFVESFVALKKLKDLTLLGNSLGGHVGLVYTLDNPDMVKRLVLTGSSGLFE
DSMGGSFPKRGNYDYVEERVGYTFYDPKTATKELVDEVFSITNSNSKCLRIIAIAKSAQR
HNMAKDITNIKVPTLLIWGLNDTITPPLVAYEFNRLMEGSELYFIDKCGHAPMMEHPEKF
NSILDKFLAKTPITTSV