Protein Info for CA264_15180 in Pontibacter actiniarum KMM 6156, DSM 19842

Annotation: energy transducer TonB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 276 transmembrane" amino acids 36 to 56 (21 residues), see Phobius details PF03544: TonB_C" amino acids 198 to 275 (78 residues), 72.7 bits, see alignment E=1.5e-24 TIGR01352: TonB family C-terminal domain" amino acids 200 to 276 (77 residues), 49.5 bits, see alignment E=2.1e-17

Best Hits

Predicted SEED Role

"Ferric siderophore transport system, periplasmic binding protein TonB" in subsystem Campylobacter Iron Metabolism or Hemin transport system or Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9YUY5 at UniProt or InterPro

Protein Sequence (276 amino acids)

>CA264_15180 energy transducer TonB (Pontibacter actiniarum KMM 6156, DSM 19842)
MDASKLAKASLDDIVFEGRNRAYGAYLLRKLYNKHITIAAIVAILLFALFLSIPLISKVL
GNDEADDEVVERIVTEVDLAPPPPLDEATPPPPPPPPPDLPPPPPPVRATVKYTPPVVKR
DNEVAEEEEIPDVEVLEEIDAGVKTVEGSKDAPIDLGDIDGTSDVVAEVVEEKPYTYVEQ
MPSFPGGETEMLKYLGKNIRYPAAAQRAGVEGLVVLSFVVSKTGEISDIQVVKNLGAGTD
EEAMRVVKTMPKWTPGKQNGRAVPVRYTLPVRFTIK