Protein Info for CA264_15120 in Pontibacter actiniarum KMM 6156, DSM 19842

Annotation: ribosome biogenesis GTPase Der

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 437 PF00009: GTP_EFTU" amino acids 5 to 166 (162 residues), 35.1 bits, see alignment E=5.7e-12 amino acids 210 to 347 (138 residues), 40.4 bits, see alignment E=1.3e-13 TIGR03594: ribosome-associated GTPase EngA" amino acids 5 to 435 (431 residues), 540.8 bits, see alignment E=4e-166 PF04548: AIG1" amino acids 6 to 109 (104 residues), 30.5 bits, see alignment E=1.3e-10 PF02421: FeoB_N" amino acids 6 to 160 (155 residues), 50.8 bits, see alignment E=7.6e-17 amino acids 179 to 307 (129 residues), 43.6 bits, see alignment E=1.2e-14 PF01926: MMR_HSR1" amino acids 6 to 121 (116 residues), 98.8 bits, see alignment E=1.2e-31 amino acids 179 to 297 (119 residues), 88.3 bits, see alignment E=2.1e-28 TIGR00231: small GTP-binding protein domain" amino acids 6 to 161 (156 residues), 69.7 bits, see alignment E=3.8e-23 amino acids 177 to 317 (141 residues), 84.8 bits, see alignment E=8.5e-28 PF14714: KH_dom-like" amino acids 355 to 435 (81 residues), 109.9 bits, see alignment E=3.2e-35

Best Hits

Swiss-Prot: 65% identical to DER_CYTH3: GTPase Der (der) from Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469)

KEGG orthology group: K03977, GTP-binding protein (inferred from 68% identity to sli:Slin_5226)

Predicted SEED Role

"GTP-binding protein EngA" in subsystem Universal GTPases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9YUY4 at UniProt or InterPro

Protein Sequence (437 amino acids)

>CA264_15120 ribosome biogenesis GTPase Der (Pontibacter actiniarum KMM 6156, DSM 19842)
MSSNIIAIVGRPNVGKSTLFNRLIGQRKAIMDNVSGVTRDRSYGHGDWTGKYYTVIDTGG
YVHGSEDIFESEINRQVELAMNEADVILFMVDVDAGLTGLDEEFANVLRRTDKPVYVVAN
KADTNARMHQMGEFYALGVGIDIYPISSQSGSGTGELLDEVVKHFKDEGVEDPDAGIPKI
AVLGRPNVGKSSFVNLLLGEERNIVTDRAGTTRDAIHARYNAFGKEFIIVDTAGLRRKSK
VSEDIEFYSVLRSVRALEDADVCIVILDATRGIEAQDVNIIALAEKNRKGIVILVNKWDL
VEKDTHTTKQFEDEIYNRIAPISYVPIIFTSVVTKQRIHKAIEVAMEVYDNKTKKIPTSK
LNDAMLPEIERYPPPAIKGKFVKIKYITQLPTHNPTFAFFCNLPQYVKESYVRYLENRMR
EHFGFTGVPIKLVFRKK